2. Gene
  3. ENPP6 - ectonucleotide pyrophosphatase/phosphodiesterase 6 Gene

ENPP6 - ectonucleotide pyrophosphatase/phosphodiesterase 6 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：外核苷酸焦磷酸酶/磷酸二酯酶 6

种属: Homo sapiens

同用名: NPP6

基因 ID: 133121 | 基因类型: protein coding

关于 ENPP6

Cytogenetic location: 4q35.1 Genomic coordinates (GRCh38): 4:184,088,706-184,217,873 (from NCBI)

This gene has 4 transcripts (splice variants), 221 orthologues and 6 paralogues. Biased expression in kidney (RPKM 13.7), ovary (RPKM 7.0) and 5 other tissues.

功能概要

启用甘油磷酸胆碱胆碱磷酸二酯酶活性。参与胆碱代谢过程和脂质代谢过程。位于细胞外区和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables glycerophosphocholine cholinephosphodiesterase activity. Involved in choline metabolic process and lipid metabolic process. Located in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ENPP6 基因产物(1)

mRNA Protein Name
NM_153343.4 NP_699174.1 glycerophosphocholine cholinephosphodiesterase ENPP6 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glycerophosphocholine cholinephosphodiesterase activity EXP
EXP: 通过实验结果推断
15788404 GOA
enables glycerophosphocholine cholinephosphodiesterase activity IDA
IDA: 通过直接分析推断
15788404 GOA
enables phosphoric diester hydrolase activity IDA
IDA: 通过直接分析推断
15788404 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in choline metabolic process IDA
IDA: 通过直接分析推断
15788404 GOA
involved in lipid metabolic process IDA
IDA: 通过直接分析推断
15788404 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
15788404 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
15788404 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ENPP6 蛋白结构

Phosphodiest

Phosphodiest: Type I phosphodiesterase / nucleotide pyrophosphatase (26 - 357)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 440 a.a.
蛋白主名 其他名称

glycerophosphocholine cholinephosphodiesterase ENPP6

B830047L21Rik

关联疾病

疾病名称 别名
Bartter Syndrome, Type 1, Antenatal

Hyperprostaglandin E Syndrome 1

Bartter Disease Type 1

BARTS1

Bartter Syndrome, Type 1

Bartter Syndrome Type 1

Hypokalemic Alkalosis With Hypercalciuria Antenatal 1

Hypokalemic Alkalosis With Hypercalciuria 1, Antenatal

Bartter Syndrome Type 1 Antenatal

Hypokalemic Alkalosis With Hypercalciuria 1 Antenatal

Bartter Syndrome Antenatal Type 1

Antenatal Bartter Syndrome Type 1

Bartter Syndrome Type I

Bartter Syndrome 1, Antenatal

Abs1

Antenatal Bartter Syndrome 1

Bs1

Bartter Syndrome, Antenatal Type 1

Antley-Bixler Syndrome With Genital Anomalies And Disordered Steroidogenesis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04392 ENPP6 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ENPP6 RGD RGD:1311645
Canis familiaris ENPP6 VGNC VGNC:40377
Macaca mulatta ENPP6 VGNC VGNC:72089
Mus musculus ENPP6 MGD MGI:2445171
Felis catus ENPP6 VGNC VGNC:61876
Bos taurus ENPP6 VGNC VGNC:28507
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