2. Gene
  3. Dhcr7 - 7-dehydrocholesterol reductase Gene

Dhcr7 - 7-dehydrocholesterol reductase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 13360 | 基因类型: protein coding

关于 Dhcr7

功能概要

Enables 7-dehydrocholesterol reductase activity. Acts upstream of or within several processes, including blood vessel development; lung development; and sterol biosynthetic process. Predicted to be located in endoplasmic reticulum and nuclear outer membrane. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in adrenal gland; genitourinary system; and neural retina. Used to study Smith-Lemli-Opitz syndrome. Human ortholog(s) of this gene implicated in Smith-Lemli-Opitz syndrome. Orthologous to human DHCR7 (7-dehydrocholesterol reductase). [provided by Alliance of Genome Resources, Apr 2022]

Dhcr7 基因产物(12)

mRNA Protein Name
NM_001382498.2 NP_001369427.1 7-dehydrocholesterol reductase isoform 1
NM_001382499.1 NP_001369428.1 7-dehydrocholesterol reductase isoform 2
NM_001382500.1 NP_001369429.1 7-dehydrocholesterol reductase isoform 3
NM_001382501.2 NP_001369430.1 7-dehydrocholesterol reductase isoform 4
NM_001382503.1 NP_001369432.1 7-dehydrocholesterol reductase isoform 1
NM_001412317.1 NP_001399246.1 7-dehydrocholesterol reductase isoform 1
NM_001412318.1 NP_001399247.1 7-dehydrocholesterol reductase isoform 1
NM_001412319.1 NP_001399248.1 7-dehydrocholesterol reductase isoform 1
NM_001412320.1 NP_001399249.1 7-dehydrocholesterol reductase isoform 4
NM_001412321.1 NP_001399250.1 7-dehydrocholesterol reductase isoform 3
NM_001412322.1 NP_001399251.1 7-dehydrocholesterol reductase isoform 5
NM_007856.2 NP_031882.1 7-dehydrocholesterol reductase isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 7-dehydrocholesterol reductase activity IDA
IDA: 通过直接分析推断
11792727 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blood vessel development IMP
IMP: 通过突变表型推断
15005800 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
15005800 MGI
acts upstream of or within lung epithelial cell differentiation IMP
IMP: 通过突变表型推断
15005800 MGI
acts upstream of or within multicellular organism growth IMP
IMP: 通过突变表型推断
15005800 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
15005800 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: 通过突变表型推断
15005800 MGI
acts upstream of or within sterol biosynthetic process IMP
IMP: 通过突变表型推断
15005800 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

7-dehydrocholesterol reductase

7-DHC reductase

sterol Delta(7)-reductase

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107420 AY 9944 99.67% 否
HY-164561 TASIN-30 Inhibitor 98.67% 否
HY-Y0889A 1-(2,3-Dichlorphenyl)piperazine hydrochloride 99.98% 否
HY-Y0889 1-(2,3-Dichlorphenyl)piperazine 99.25% 否
HY-RS03727 DHCR7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17300 Dhcr7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23755 Dhcr7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dhcr7 NCBI NCBI:1717
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