1. Gene
  2. Dr1 - down-regulator of transcription 1 Gene

Dr1 - down-regulator of transcription 1 Gene

种属: Mus musculus

同用名: NC2; Dr1l; NC2beta; 1700121L09Rik

基因 ID: 13486 | 基因类型: protein coding

关于 Dr1

功能概要

Predicted to enable RNA polymerase II general transcription initiation factor activity; TBP-class protein binding activity; and core promoter sequence-specific DNA binding activity. Predicted to be involved in several processes, including RNA polymerase II preinitiation complex assembly; histone H3 acetylation; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of ATAC complex. Is expressed in central nervous system; early conceptus; genitourinary system; limb mesenchyme; and neural retina. Orthologous to human DR1 (down-regulator of transcription 1). [provided by Alliance of Genome Resources, Apr 2022]

Dr1 基因产物(1)

mRNA Protein Name
NM_026106.4 NP_080382.2 protein Dr1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19103755 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of cell cycle IMP
IMP: 通过突变表型推断
19103755 MGI
involved in regulation of cell division IDA
IDA: 通过直接分析推断
20562830 MGI
involved in regulation of embryonic development IDA
IDA: 通过直接分析推断
19103755 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ATAC complex IDA
IDA: 通过直接分析推断
19936620 MGI
located in nucleus IDA
IDA: 通过直接分析推断
19103755 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein Dr1

NC2-beta

TATA-binding protein-associated phosphoprotein

negative cofactor 2-beta

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dr1 NCBI NCBI:1810
Rattus norvegicus Dr1 NCBI NCBI:289881