2. Gene
  3. Edn2 - endothelin 2 Gene

Edn2 - endothelin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: VIC; ET-2; PPET2

基因 ID: 13615 | 基因类型: protein coding

关于 Edn2

功能概要

This gene encodes a member of the endothelin family of peptides. The encoded preproprotein undergoes proteolytic processing to generate a potent vasoconstrictive peptide. This gene is abundantly expressed in the gastrointestinal tract, strongly induced in photorecepteror cells in retinal diseases and injury, and produced by microglia and macrophages in the early stages of glaucoma. Mice lacking the encoded protein exhibit severe growth retardation, hypothermia and juvenile lethality. [provided by RefSeq, Feb 2016]

Edn2 基因产物(1)

mRNA Protein Name
NM_007902.3 NP_031928.2 endothelin-2 preproprotein
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in angiogenesis IDA
IDA: 通过直接分析推断
24043815 MGI
involved in angiogenesis IGI
IGI: 通过遗传相互作用推断
24043815 MGI
involved in axon extension IDA
IDA: 通过直接分析推断
18401410 MGI
involved in cell tip growth IDA
IDA: 通过直接分析推断
24043815 MGI
involved in endothelial cell migration IDA
IDA: 通过直接分析推断
24043815 MGI
acts upstream of or within energy homeostasis IMP
IMP: 通过突变表型推断
23676500 MGI
acts upstream of or within lung alveolus development IMP
IMP: 通过突变表型推断
23676500 MGI
involved in neuron projection development IDA
IDA: 通过直接分析推断
24875861 MGI
involved in positive regulation of prostaglandin-endoperoxide synthase activity IMP
IMP: 通过突变表型推断
9492062 MGI
acts upstream of or within positive regulation of smooth muscle contraction IDA
IDA: 通过直接分析推断
2768235 MGI
involved in prostaglandin biosynthetic process IDA
IDA: 通过直接分析推断
9492062 MGI
acts upstream of smooth muscle contraction IDA
IDA: 通过直接分析推断
2768235 MGI
acts upstream of or within temperature homeostasis IMP
IMP: 通过突变表型推断
23676500 MGI
involved in vasculature development IDA
IDA: 通过直接分析推断
24043815 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

endothelin-2

preproendothelin-2

vasoactive intestinal contractor peptide

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04164 EDN2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22152 Edn2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Edn2 NCBI NCBI:1907
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