1. Gene
  2. GPAT4 - glycerol-3-phosphate acyltransferase 4 Gene

GPAT4 - glycerol-3-phosphate acyltransferase 4 Gene

中文名称:3-磷酸甘油酰基转移酶 4

种属: Homo sapiens

同用名: AGPAT6; LPAATZ; TSARG7; 1-AGPAT 6; LPAAT-zeta

基因 ID: 137964 | 基因类型: protein coding

关于 GPAT4

Cytogenetic location: 8p11.21 Genomic coordinates (GRCh38): 8:41,578,200-41,625,001 (from NCBI)

This gene has 11 transcripts (splice variants), 271 orthologues and 4 paralogues. Ubiquitous expression in endometrium (RPKM 10.2), adrenal (RPKM 10.1) and 25 other tissues.

功能概要

溶血磷脂酸酰基转移酶 (EC 2.3.1.51) 催化溶血磷脂酸 (LPA) 向磷脂酸 (PA) 的转化。 LPA 和 PA 参与信号转导和脂质生物合成。[OMIM 提供,2004 年 4 月]

Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.[supplied by OMIM, Apr 2004]

GPAT4 基因产物(3)

mRNA Protein Name
NM_001363197.2 NP_001350126.1 glycerol-3-phosphate acyltransferase 4 isoform 1 precursor
NM_001363198.2 NP_001350127.1 glycerol-3-phosphate acyltransferase 4 isoform 2
NM_178819.4 NP_848934.1 glycerol-3-phosphate acyltransferase 4 isoform 1 precursor

GPAT4 蛋白结构

Acyltransferase

Acyltransferase: Acyltransferase (229 - 351)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 456 a.a.
蛋白主名 其他名称

glycerol-3-phosphate acyltransferase 4

1-AGP acyltransferase 6

关联疾病

疾病名称 别名
Spastic Monoplegia

Monoplegic Infantile Cerebral Palsy

Spastic Monoplegic Cerebral Palsy

Infantile Monoplegic Cerebral Palsy

Cerebral Palsy Spastic Monoplegic

Spastic Monoplegia Cerebral Palsy

Complete Generalized Lipodystrophy
Congenital Generalized Lipodystrophy

Berardinelli-Seip Congenital Lipodystrophy

Berardinelli-Seip Syndrome

Brunzell Syndrome

Bscl

Generalized Lipodystrophy

Lipodystrophy, Congenital Generalized

Seip Syndrome

Total Lipodystrophy

Cgl

Lipoatrophic Diabetes

Lipodystrophy, Generalized, Congenital

Familial Generalized Lipodystrophy

Congenital Generalized Lipodystrophy Type 2

Lipoatrophic Diabetes Mellitus

Familial Partial Lipodystrophy, Type 2

Lipodystrophy, Congenital Generalized, Type 2

Congenital Generalized Lipodystrophy Type 2

CGL2

Berardinelli-Seip Congenital Lipodystrophy Type 2

Berardinelli-Seip Syndrome

Brunzell Syndrome Bscl2-Related

Total Lipodystrophy And Acromegaloid Gigantism

Berardinelli-Seip Congenital Lipodystrophy, Type 2

Seip Syndrome

Berardinelli Syndrome

Lipodystrophy, Total, And Acromegaloid Gigantism

Lipoatrophic Diabetes, Congenital

Lipodystrophy, Berardinelli-Seip Congenital, Type 2

Brunzell Syndrome, Bscl2-Related

Congenital Lipoatrophic Diabetes

Congenital Generalized Lipodystrophy 2

Lipoatrophic Diabetes

Lipodystrophy Berardinelli Type

Familial Generalized Lipodystrophy

Lipoatrophic Diabetes Mellitus

Familial Partial Lipodystrophy, Type 2

Fetal Akinesia Deformation Sequence 1

Fetal Akinesia Deformation Sequence

Fads

Fetal Akinesia Sequence

FADS1

Arthrogryposis Multiplex Congenita With Pulmonary Hypoplasia

Pena-Shokeir Syndrome Type 1

Fetal Akinesia Deformation Sequence Syndrome

Arthrogryposis Multiplex Congenita-Pulmonary Hypoplasia Syndrome

Arthrogryposis Multiplex Congenita Pulmonary Hypoplasia

Pena-Shokeir Syndrome, Type I

Foetal Akinesia Deformation Sequence Syndrome

Foetal Akinesia Sequence

Fetal Akinesia Deformation Sequence Syndrome 1

Pena-Shokeir Syndrome, Type 1

Pena Shokeir Syndrome, Type 1

Akinesia, Fetal, Deformation Sequence

Akinesia, Fetal, Deformation Sequence, Type 1

Pena-Shokeir Syndrome Type I

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus GPAT4 VGNC VGNC:62655
Rattus norvegicus GPAT4 RGD RGD:1310520
Canis familiaris GPAT4 VGNC VGNC:49765
Macaca mulatta GPAT4 VGNC VGNC:84002
Mus musculus GPAT4 MGD MGI:2142716
Others GPAT4 NCBI