2. Gene
  3. Erf - Ets2 repressor factor Gene

Erf - Ets2 repressor factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 13875 | 基因类型: protein coding

关于 Erf

功能概要

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within chorio-allantoic fusion; ectodermal cell differentiation; and trophoblast giant cell differentiation. Located in nucleus. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Human ortholog(s) of this gene implicated in craniosynostosis. Orthologous to human ERF (ETS2 repressor factor). [provided by Alliance of Genome Resources, Apr 2022]

Erf 基因产物(4)

mRNA Protein Name
NM_001412415.1 NP_001399344.1 ETS domain-containing transcription factor ERF isoform a
NM_001412417.1 NP_001399346.1 ETS domain-containing transcription factor ERF isoform c
NM_001412418.1 NP_001399347.1 ETS domain-containing transcription factor ERF isoform c
NM_010155.4 NP_034285.3 ETS domain-containing transcription factor ERF isoform b
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within chorio-allantoic fusion IMP
IMP: 通过突变表型推断
17502352 MGI
acts upstream of or within ectodermal cell differentiation IMP
IMP: 通过突变表型推断
17502352 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
17502352 MGI
acts upstream of or within trophoblast giant cell differentiation IMP
IMP: 通过突变表型推断
17502352 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
17502352 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ETS domain-containing transcription factor ERF

Est2 repressor factor

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-150090 SRI-41315 Activator 99.68% 否
HY-163938 PROTAC erf3a Degrader-1 99.44% 否
HY-120743 Triplin / 否
HY-153176 PAT-IN-1 Inhibitor / 否
HY-153177 PAT-IN-2 Inhibitor / 否
HY-163938A PROTAC erf3a Degrader-2 / 否
HY-163960 NH2-Ph-NH-cyclohexane-NH-Boc / 否
HY-163961A Thalidomide-NH-cyclohexane-NH-Ph-NH2 / 否
HY-RS04488 ERF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04554 ETF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16710 Erf Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20729 Etf1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23145 Erf Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Erf NCBI NCBI:2077
Canis familiaris Erf NCBI NCBI:100687937
Macaca fascicularis Erf NCBI NCBI:102115865
Canis lupus familiaris Erf NCBI
Susscrofa domestica Erf NCBI
Leporidae Erf NCBI
Rattus norvegicus Erf NCBI NCBI:292721
Macaca mulatta Erf NCBI NCBI:709170
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