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  3. MAGEC3 - MAGE family member C3 Gene

MAGEC3 - MAGE family member C3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：MAGE 家族成员 C3

种属: Homo sapiens

同用名: HCA2; CT7.2; MAGEC4; MAGE-C3

基因 ID: 139081 | 基因类型: protein coding

关于 MAGEC3

Cytogenetic location: Xq27.2 Genomic coordinates (GRCh38): X:141,838,316-141,897,832 (from NCBI)

This gene has 5 transcripts (splice variants), 466 orthologues and 37 paralogues. Low expression observed in reference dataset.

功能概要

该基因是 MAGEC 基因家族的成员。该家族的成员在除睾丸外的正常组织中不表达，并在各种组织学类型的肿瘤中表达。 MAGEC 基因聚集在染色体 Xq26-q27 上。已发现该基因的两个转录变体编码不同的亚型。[RefSeq 提供，2008 年 7 月]

This gene is a member of the MAGEC gene family. The members of this family are not expressed in normal tissues, except for testis, and are expressed in tumors of various histological types. The MAGEC genes are clustered on chromosome Xq26-q27. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

MAGEC3 基因产物(2)

mRNA Protein Name
NM_138702.1 NP_619647.1 melanoma-associated antigen C3 isoform 1
NM_177456.2 NP_803251.1 melanoma-associated antigen C3 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MAGEC3 蛋白结构

MAGE

MAGE: MAGE family (191 - 303)

MAGE

MAGE: MAGE family (463 - 576)

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  • 643 a.a.
蛋白主名 其他名称

melanoma-associated antigen C3

MAGE family testis and tumor-specific protein

关联疾病

疾病名称 别名
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Adult Hepatocellular Carcinoma

Adult Primary Hepatocellular Carcinoma

Adult Hepatoma

Adult Hcc
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07975 MAGEC3 Human Pre-designed siRNA Set A Pre-designed Set / 否
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