2. Gene
  3. Etv6 - ets variant 6 Gene

Etv6 - ets variant 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tel

基因 ID: 14011 | 基因类型: protein coding

关于 Etv6

功能概要

This gene encodes a transcriptional repressor belonging to the ETS family of proteins. Knockout of this gene in mice results in embryonic lethality due to defective angiogenesis. In humans, this gene is often involved in chromosome rearrangements associated with specific cancers. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Etv6 基因产物(2)

mRNA Protein Name
NM_001303102.1 NP_001290031.1 transcription factor ETV6 isoform 2
NM_007961.4 NP_031987.3 transcription factor ETV6 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12527908 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
17606295 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
12527908 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17606295 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12527908 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell differentiation IDA
IDA: 通过直接分析推断
12527908 MGI
acts upstream of or within mesenchymal cell apoptotic process IMP
IMP: 通过突变表型推断
9250681 MGI
acts upstream of or within neurogenesis IMP
IMP: 通过突变表型推断
9250681 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
17606295 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12527908 MGI
acts upstream of or within vitellogenesis IMP
IMP: 通过突变表型推断
9250681 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor ETV6

ETS-related protein Tel1

ets variant gene 6 (TEL oncogene)

translocation-ets-leukemia

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-146807 Type II TRK inhibitor 1 Inhibitor / 否
HY-155046 FGFR4-IN-14 Inhibitor / 否
HY-163366 TRK-IN-28 Inhibitor / 否
HY-RS04569 ETV6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19598 Etv6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26094 Etv6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Etv6 NCBI NCBI:2120
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