MUC17 - mucin 17, cell surface associated Gene

中文名称：粘蛋白 17，细胞表面相关

种属: Homo sapiens

同用名: MUC3; MUC-3; MUC-17

关于 MUC17

功能概要

该基因编码的蛋白质是一种膜结合粘蛋白，可为肠上皮细胞提供保护。编码的蛋白质包含约 60 个串联重复，每个重复约 60 个氨基酸。 N-糖基化使编码的蛋白质定位于细胞表面，而 C-末端与支架蛋白 PDZ 结构域包含 1 (PDZK1) 相互作用。已发现该基因的两种转录变体，一种是蛋白质编码，另一种是非蛋白质编码。[RefSeq 提供，2015 年 11 月]

The protein encoded by this gene is a membrane-bound Mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]