1. Gene
  2. Ryk - receptor-like tyrosine kinase Gene

Ryk - receptor-like tyrosine kinase Gene

种属: Rattus norvegicus

基因 ID: 140585 | 基因类型: protein coding

关于 Ryk

功能概要

Predicted to enable Wnt-activated receptor activity; Wnt-protein binding activity; and Frizzled binding activity. Predicted to be involved in several processes, including nervous system development; positive regulation of MAPK cascade; and positive regulation of kinase activity. Predicted to act upstream of or within several processes, including generation of neurons; negative chemotaxis; and skeletal system morphogenesis. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Orthologous to human RYK (receptor like tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Ryk 基因产物(1)

mRNA Protein Name
NM_080402.2 NP_536327.1 tyrosine-protein kinase RYK precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Wnt signaling pathway IMP
IMP: 通过突变表型推断
23517308 RGD
involved in axonogenesis IGI
IGI: 通过遗传相互作用推断
23517308 RGD
involved in positive regulation of cell proliferation in midbrain IMP
IMP: 通过突变表型推断
23517308 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tyrosine-protein kinase RYK

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ryk NCBI NCBI:6259