2. Gene
  3. Sox9 - SRY-box transcription factor 9 Gene

Sox9 - SRY-box transcription factor 9 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: SRY

基因 ID: 140586 | 基因类型: protein coding

关于 Sox9

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; bHLH transcription factor binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including Sertoli cell development; cAMP-mediated signaling; and positive regulation of macromolecule metabolic process. Part of transcription regulator complex. Human ortholog(s) of this gene implicated in 46,XX sex reversal 2; 46,XY sex reversal 10; and campomelic dysplasia. Orthologous to human SOX9 (SRY-box transcription factor 9). [provided by Alliance of Genome Resources, Apr 2022]

Sox9 基因产物(1)

mRNA Protein Name
NM_080403.2 NP_536328.1 transcription factor SOX-9
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
11875113 RGD
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
11514554 RGD
enables bHLH transcription factor binding IPI
IPI: 通过物理相互作用推断
19828133 RGD
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
10805756 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Sertoli cell development IEP
IEP: 通过表达模式推断
11875113 RGD
involved in cAMP-mediated signaling IDA
IDA: 通过直接分析推断
10805756 RGD
involved in cartilage development IEP
IEP: 通过表达模式推断
15512770 RGD
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
19828133 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11875113 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
30599193 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of transcription regulator complex IDA
IDA: 通过直接分析推断
19828133 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor SOX-9

SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)

SRY box 9

SRY-box containing gene 9

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13599 SOX9 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17376 Sox9 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23830 Sox9 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sox9 NCBI NCBI:6662
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