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  2. Gpr6 - G protein-coupled receptor 6 Gene

Gpr6 - G protein-coupled receptor 6 Gene

中文名称:G 蛋白偶联受体 6

种属: Mus musculus

同用名: Gm233

基因 ID: 140741 | 基因类型: protein coding

关于 Gpr6

Chromosome 10: 40,945,973-40,948,281 reverse strand.GRCm39:CM001003.3

This gene has 1 transcript (splice variant), 186 orthologues, 18 paralogues and is associated with 3 phenotypes. Biased expression in cortex adult (RPKM 1.6), CNS E18 (RPKM 1.2) and 7 other tissues.

功能概要

该基因编码的蛋白可启动 1- 磷酸鞘氨醇受体活性。在细胞溶质钙离子浓度的正调节上游或正调节内起作用。预测位于膜中。预计是膜的组成部分。预计在细胞质和质膜中有活性。以多种结构表达,包括消化系统;眼睛;免疫系统;雄性生殖腺或器官;和神经系统。与人类 GPR6(G 蛋白偶联受体 6)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables sphingosine-1-phosphate receptor activity. Acts upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; eye; immune system; male reproductive gland or organ; and nervous system. Orthologous to human GPR6 (G protein-coupled receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Gpr6 基因产物(1)

mRNA Protein Name
NM_199058.2 NP_951013.1 G-protein coupled receptor 6
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sphingosine-1-phosphate receptor activity IDA
IDA: 通过直接分析推断
14592418 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
14592418 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Gpr6 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (73 - 340)

7tm_GPCRs

7tm_GPCRs: cd14964 (75 - 99)

7tm_GPCRs

7tm_GPCRs: cd14964 (108 - 129)

7tm_GPCRs

7tm_GPCRs: cd14964 (142 - 164)

7tm_GPCRs

7tm_GPCRs: cd14964 (187 - 203)

7tm_GPCRs

7tm_GPCRs: cd14964 (223 - 246)

7tm_GPCRs

7tm_GPCRs: cd14964 (278 - 300)

7tm_GPCRs

7tm_GPCRs: cd14964 (308 - 333)

  • 0
  • 100
  • 200
  • 300
  • 363 a.a.
蛋白主名 其他名称

G-protein coupled receptor 6

sphingosine 1-phosphate receptor GPR6

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpr6 NCBI NCBI:2830