2. Gene
  3. Fanca - Fanconi anemia, complementation group A Gene

Fanca - Fanconi anemia, complementation group A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: FACA

基因 ID: 14087 | 基因类型: protein coding

关于 Fanca

功能概要

Acts upstream of or within several processes, including gonad development; regulation of CD40 signaling pathway; and regulation of regulatory T cell differentiation. Predicted to be located in nucleoplasm. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including gut; liver; lung; reproductive system; and spleen. Used to study Fanconi anemia complementation group A. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple); acute myeloid leukemia; esophagus squamous cell carcinoma; ovarian disease (multiple); and skin melanoma. Orthologous to human FANCA (FA complementation group A). [provided by Alliance of Genome Resources, Apr 2022]

Fanca 基因产物(1)

mRNA Protein Name
NM_016925.4 NP_058621.2 Fanconi anemia group A protein homolog
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within female gonad development IMP
IMP: 通过突变表型推断
12913077 MGI
acts upstream of or within male gonad development IMP
IMP: 通过突变表型推断
12913077 MGI
acts upstream of or within male meiotic nuclear division IMP
IMP: 通过突变表型推断
12913077 MGI
acts upstream of or within regulation of CD40 signaling pathway IMP
IMP: 通过突变表型推断
24501220 MGI
acts upstream of or within regulation of DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
24501220 MGI
acts upstream of or within regulation of germ cell proliferation IMP
IMP: 通过突变表型推断
12913077 MGI
acts upstream of or within regulation of inflammatory response IMP
IMP: 通过突变表型推断
24501220 MGI
acts upstream of or within regulation of regulatory T cell differentiation IMP
IMP: 通过突变表型推断
24501220 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Fanconi anemia group A protein homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04732 FANCA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19192 Fanca Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25680 Fanca Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fanca NCBI NCBI:2175
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