2. Gene
  3. Fancc - Fanconi anemia, complementation group C Gene

Fancc - Fanconi anemia, complementation group C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Facc

基因 ID: 14088 | 基因类型: protein coding

关于 Fancc

功能概要

Acts upstream of or within several processes, including brain morphogenesis; neuronal stem cell population maintenance; and removal of superoxide radicals. Predicted to be located in chromatin and cytosol. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; reproductive system; retina nuclear layer; and skeleton. Used to study Fanconi anemia complementation group C. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple); acute myeloid leukemia; aspirin-induced respiratory disease; pancreatic cancer; and pancytopenia. Orthologous to human FANCC (FA complementation group C). [provided by Alliance of Genome Resources, Apr 2022]

Fancc 基因产物(5)

mRNA Protein Name
NM_001042673.2 NP_001036138.1 Fanconi anemia group C protein homolog isoform 1
NM_001282942.1 NP_001269871.1 Fanconi anemia group C protein homolog isoform 2
NM_001347514.1 NP_001334443.1 Fanconi anemia group C protein homolog isoform 3
NM_001347515.1 NP_001334444.1 Fanconi anemia group C protein homolog isoform 4 precursor
NM_007985.3 NP_032011.2 Fanconi anemia group C protein homolog isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within brain morphogenesis IGI
IGI: 通过遗传相互作用推断
24483844 MGI
acts upstream of or within cellular response to oxidative stress IGI
IGI: 通过遗传相互作用推断
24483844 MGI
acts upstream of or within gamete generation IMP
IMP: 通过突变表型推断
8630504 MGI
acts upstream of or within germ cell development IMP
IMP: 通过突变表型推断
8704201 MGI
acts upstream of or within myeloid cell homeostasis IGI
IGI: 通过遗传相互作用推断
11493445 MGI
acts upstream of or within myeloid cell homeostasis IMP
IMP: 通过突变表型推断
11493445 MGI
acts upstream of or within neuronal stem cell population maintenance IGI
IGI: 通过遗传相互作用推断
24483844 MGI
acts upstream of or within nucleotide-excision repair IMP
IMP: 通过突变表型推断
8704201 MGI
acts upstream of or within removal of superoxide radicals IGI
IGI: 通过遗传相互作用推断
11493445 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Fanconi anemia group C protein homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04734 FANCC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20402 Fancc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26911 Fancc Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fancc NCBI NCBI:2176
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