2. Gene
  3. Fat1 - FAT atypical cadherin 1 Gene

Fat1 - FAT atypical cadherin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fath; mFat1; 2310038E12Rik

基因 ID: 14107 | 基因类型: protein coding

关于 Fat1

功能概要

Involved in epithelial cell morphogenesis; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis; and lens development in camera-type eye. Acts upstream of or within actin filament organization; cell-cell adhesion; and establishment or maintenance of cell polarity. Located in several cellular components, including apical plasma membrane; filopodium; and lamellipodium. Is active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; embryo mesenchyme; and sensory organ. Used to study facioscapulohumeral muscular dystrophy and nephrotic syndrome. Orthologous to human FAT1 (FAT atypical Cadherin 1). [provided by Alliance of Genome Resources, Apr 2022]

Fat1 基因产物(1)

mRNA Protein Name
NM_001081286.2 NP_001074755.2 protocadherin Fat 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15148305 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin filament organization IMP
IMP: 通过突变表型推断
15148305 MGI
involved in camera-type eye development IMP
IMP: 通过突变表型推断
26114487 MGI
involved in camera-type eye morphogenesis IMP
IMP: 通过突变表型推断
26114487 MGI
acts upstream of or within cell-cell adhesion IMP
IMP: 通过突变表型推断
15148305 MGI
involved in epithelial cell morphogenesis IMP
IMP: 通过突变表型推断
26114487 MGI
involved in establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis IMP
IMP: 通过突变表型推断
26114487 MGI
acts upstream of or within establishment or maintenance of cell polarity IMP
IMP: 通过突变表型推断
15148305 MGI
involved in establishment or maintenance of epithelial cell apical/basal polarity IMP
IMP: 通过突变表型推断
26114487 MGI
involved in lens development in camera-type eye IMP
IMP: 通过突变表型推断
26114487 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in apical plasma membrane IDA
IDA: 通过直接分析推断
26114487 MGI
located in cell junction IDA
IDA: 通过直接分析推断
15148305 MGI
located in filopodium IDA
IDA: 通过直接分析推断
15148305 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
15148305 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
26114487 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protocadherin Fat 1

FAT tumor suppressor homolog 1

fat 1 cadherin

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-115319 CP-24879 hydrochloride 99.59% 否
HY-124141 Myristelaidic acid ≥98.0% 否
HY-135297 Mono-and diglycerides 97.50% 否
HY-B1567 Bromocyclen / 否
HY-RS04760 FAT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W753983 Pyruvic acid-13C3 / 否
HY-Y0781S6 Pyruvic acid-13C-4 / 否
HY-116846 Methyldymron / 否
HY-168386 1,2-Dipalmitoyl-3-Myristoyl-rac-glycerol / 否
HY-RS18131 Fat1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24605 Fat1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fat1 NCBI NCBI:2195
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z