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  2. Ms4a2 - membrane-spanning 4-domains, subfamily A, member 2 Gene

Ms4a2 - membrane-spanning 4-domains, subfamily A, member 2 Gene

种属: Mus musculus

同用名: FcRB; Fce1b; Ms4a1; fcERI; Fcer1b; Fcrbeta

基因 ID: 14126 | 基因类型: protein coding

关于 Ms4a2

功能概要

This gene encodes a member of the membrane-spanning 4A family. The encoded protein is the beta subunit of the high affinity IgE receptor and is localized to the membrane. The encoded protein is required for full activation of mast cells, including the release of histamine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Ms4a2 基因产物(4)

mRNA Protein Name
NM_001276328.1 NP_001263257.1 high affinity immunoglobulin epsilon receptor subunit beta isoform b
NM_001276329.1 NP_001263258.1 high affinity immunoglobulin epsilon receptor subunit beta isoform c
NM_001276330.1 NP_001263259.1 high affinity immunoglobulin epsilon receptor subunit beta isoform d
NM_013516.2 NP_038544.1 high affinity immunoglobulin epsilon receptor subunit beta isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to IgE binding IDA
IDA: 通过直接分析推断
14764707 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
9000133 MGI
acts upstream of or within signal transduction IDA
IDA: 通过直接分析推断
12192036 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Fc-epsilon receptor I complex IDA
IDA: 通过直接分析推断
14764707 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
2527850 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
2527850 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

high affinity immunoglobulin epsilon receptor subunit beta

Fc receptor, IgE, high affinity I, beta polypeptide

fc epsilon receptor I beta-chain

membrane-spanning 4-domains, subfamily A, member 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ms4a2 NCBI NCBI:2206
Macaca fascicularis Ms4a2 NCBI NCBI:102127416
Canis lupus familiaris Ms4a2 NCBI