1. Gene
  2. Fgf13 - fibroblast growth factor 13 Gene

Fgf13 - fibroblast growth factor 13 Gene

种属: Mus musculus

同用名: Fhf2; Fgf1c

基因 ID: 14168 | 基因类型: protein coding

关于 Fgf13

功能概要

Enables Sodium Channel regulator activity; transmembrane transporter binding activity; and tubulin binding activity. Involved in several processes, including learning or memory; nervous system development; and regulation of cardiac muscle cell action potential involved in regulation of contraction. Located in several cellular components, including growth cone; intercalated disc; and lateral plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and sensory organ. Used to study intellectual disability. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy. Orthologous to human FGF13 (Fibroblast Growth Factor 13). [provided by Alliance of Genome Resources, Apr 2022]

Fgf13 基因产物(7)

mRNA Protein Name
NM_001290414.1 NP_001277343.1 fibroblast growth factor 13 isoform 2
NM_001290415.1 NP_001277344.1 fibroblast growth factor 13 isoform 3
NM_001356335.1 NP_001343264.1 fibroblast growth factor 13 isoform 4
NM_001411971.1 NP_001398900.1 fibroblast growth factor 13 isoform 2
NM_001411972.1 NP_001398901.1 fibroblast growth factor 13 isoform 2
NM_001411973.1 NP_001398902.1 fibroblast growth factor 13 isoform 2
NM_010200.3 NP_034330.2 fibroblast growth factor 13 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-tubulin binding IDA
IDA: 通过直接分析推断
22726441 MGI
enables microtubule binding IDA
IDA: 通过直接分析推断
22726441 MGI
enables sodium channel regulator activity IMP
IMP: 通过突变表型推断
21817159 MGI
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
21817159 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
NOT involved in apoptotic process IMP
IMP: 通过突变表型推断
22726441 MGI
acts upstream of or within branching morphogenesis of a nerve IMP
IMP: 通过突变表型推断
34184986 MGI
involved in cerebral cortex cell migration IMP
IMP: 通过突变表型推断
22726441 MGI
NOT involved in establishment of neuroblast polarity IMP
IMP: 通过突变表型推断
22726441 MGI
involved in establishment of neuroblast polarity IMP
IMP: 通过突变表型推断
22726441 MGI
involved in hippocampus development IMP
IMP: 通过突变表型推断
22726441 MGI
involved in inhibitory synapse assembly IMP
IMP: 通过突变表型推断
30679375 MGI
involved in learning IMP
IMP: 通过突变表型推断
22726441 MGI
acts upstream of or within learning or memory IMP
IMP: 通过突变表型推断
34184986 MGI
involved in memory IMP
IMP: 通过突变表型推断
22726441 MGI
involved in microtubule polymerization IMP
IMP: 通过突变表型推断
22726441 MGI
involved in negative regulation of collateral sprouting IMP
IMP: 通过突变表型推断
22726441 MGI
involved in negative regulation of microtubule depolymerization IMP
IMP: 通过突变表型推断
22726441 MGI
acts upstream of or within neurogenesis IMP
IMP: 通过突变表型推断
34010636 MGI
NOT involved in neuron migration IMP
IMP: 通过突变表型推断
22726441 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
34184986 MGI
involved in neuron migration IMP
IMP: 通过突变表型推断
22726441 MGI
involved in protein localization to plasma membrane IMP
IMP: 通过突变表型推断
21817159 MGI
involved in regulation of cardiac muscle cell action potential involved in regulation of contraction IMP
IMP: 通过突变表型推断
21817159 MGI
involved in sodium ion transport IMP
IMP: 通过突变表型推断
21817159 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
22726441 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
21817159 MGI
located in cytosol IDA
IDA: 通过直接分析推断
10644718 MGI
located in dendrite IDA
IDA: 通过直接分析推断
22726441 MGI
located in filopodium IDA
IDA: 通过直接分析推断
22726441 MGI
located in growth cone IDA
IDA: 通过直接分析推断
22726441 MGI
located in intercalated disc IDA
IDA: 通过直接分析推断
21817159 MGI
located in lateral plasma membrane IDA
IDA: 通过直接分析推断
21817159 MGI
located in microtubule IDA
IDA: 通过直接分析推断
22726441 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
22726441 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10644718 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
21817159 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

fibroblast growth factor 13

fibroblast growth factor 1c

fibroblast growth factor homologous factor 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fgf13 NCBI NCBI:2258