2. Gene
  3. Fhl2 - four and a half LIM domains 2 Gene

Fhl2 - four and a half LIM domains 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: FHL-2; SLIM3; SLIM-3

基因 ID: 14200 | 基因类型: protein coding

关于 Fhl2

功能概要

This gene encodes a member of the four-and-a-half-LIM-only protein family. The encoded protein functions as a regulator in numerous signaling pathways and cellular processes in development and cellular differentiation, including development and maintenance of the cardiovascular system and striated muscles. This gene also plays a role in bone formation and regulates and bone mineral content and bone mineral density. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Fhl2 基因产物(3)

mRNA Protein Name
NM_001289533.2 NP_001276462.1 four and a half LIM domains protein 2
NM_001412598.1 NP_001399527.1 four and a half LIM domains protein 2
NM_010212.5 NP_034342.1 four and a half LIM domains protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables bHLH transcription factor binding IPI
IPI: 通过物理相互作用推断
15509787 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
15509787 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in atrial cardiac muscle cell development IEP
IEP: 通过表达模式推断
15509787 MGI
involved in heart trabecula formation IEP
IEP: 通过表达模式推断
15509787 MGI
involved in negative regulation of calcineurin-NFAT signaling cascade IMP
IMP: 通过突变表型推断
22851699 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15509787 MGI
involved in osteoblast differentiation IEP
IEP: 通过表达模式推断
16311053 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12151099 MGI
involved in ventricular cardiac muscle cell development IEP
IEP: 通过表达模式推断
15509787 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
22851699 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12151099 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

four and a half LIM domains protein 2

skeletal muscle LIM-protein 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04935 FHL2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS17638 Fhl2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS24098 Fhl2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fhl2 NCBI NCBI:2274
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