2. Gene
  3. Fkbp10 - FK506 binding protein 10 Gene

Fkbp10 - FK506 binding protein 10 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fkbp6; FKBP65; Fkbprp; FKBP-10; FKBP-65; Fkbp-rs1; Fkbp1-rs

基因 ID: 14230 | 基因类型: protein coding

关于 Fkbp10

功能概要

Enables FK506 binding activity and peptidyl-prolyl cis-trans isomerase activity. Acts upstream of or within several processes, including aorta morphogenesis; extracellular matrix organization; and peptidyl-amino acid modification. Located in endoplasmic reticulum; membrane; and mitochondrial intermembrane space. Is expressed in several structures, including connective tissue; intestine epithelium; lung; metanephros; and skeleton. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 11. Orthologous to human FKBP10 (FKBP prolyl isomerase 10). [provided by Alliance of Genome Resources, Apr 2022]

Fkbp10 基因产物(2)

mRNA Protein Name
NM_001163481.1 NP_001156953.1 peptidyl-prolyl cis-trans isomerase FKBP10 isoform 2 precursor
NM_010221.2 NP_034351.2 peptidyl-prolyl cis-trans isomerase FKBP10 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables FK506 binding IDA
IDA: 通过直接分析推断
7493967 MGI
enables peptidyl-prolyl cis-trans isomerase activity IDA
IDA: 通过直接分析推断
7493967 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aorta morphogenesis IMP
IMP: 通过突变表型推断
24777781 MGI
acts upstream of or within collagen fibril organization IMP
IMP: 通过突变表型推断
24777781 MGI
acts upstream of or within extracellular matrix assembly IMP
IMP: 通过突变表型推断
28774593 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
24777781 MGI
acts upstream of or within peptidyl-lysine hydroxylation IMP
IMP: 通过突变表型推断
24777781 MGI
acts upstream of or within peptidyl-proline modification IDA
IDA: 通过直接分析推断
7493967 MGI
acts upstream of or within wound healing IMP
IMP: 通过突变表型推断
28774593 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
24777781 MGI
located in membrane IDA
IDA: 通过直接分析推断
7493967 MGI
located in mitochondrial intermembrane space IDA
IDA: 通过直接分析推断
25002142 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase FKBP10

65 kDa FK506-binding protein

65 kDa FKBP

FK506 binding protein 6 (65 kDa)

PPIase FKBP10

immunophilin FKBP65

rotamase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04956 FKBP10 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18709 Fkbp10 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25196 Fkbp10 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fkbp10 NCBI NCBI:60681
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