2. Gene
  3. Fkbp8 - FK506 binding protein 8 Gene

Fkbp8 - FK506 binding protein 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 38kDa; FKBP-8; Fkbp38; FKBP-38; FKBPR38; mFKBP38

基因 ID: 14232 | 基因类型: protein coding

关于 Fkbp8

功能概要

Enables protein folding chaperone. Acts upstream of or within several processes, including dorsal/ventral neural tube patterning; positive regulation of BMP signaling pathway; and smoothened signaling pathway. Located in mitochondrial envelope. Is integral component of endoplasmic reticulum membrane. Is expressed in embryo. Used to study clubfoot. Orthologous to human FKBP8 (FKBP prolyl isomerase 8). [provided by Alliance of Genome Resources, Apr 2022]

Fkbp8 基因产物(3)

mRNA Protein Name
NM_001111066.1 NP_001104536.1 peptidyl-prolyl cis-trans isomerase FKBP8 isoform a
NM_001199631.1 NP_001186560.1 peptidyl-prolyl cis-trans isomerase FKBP8 isoform a
NM_010223.2 NP_034353.2 peptidyl-prolyl cis-trans isomerase FKBP8 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
29916806 MGI
enables protein folding chaperone IMP
IMP: 通过突变表型推断
29916806 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of BMP signaling pathway IMP
IMP: 通过突变表型推断
18590716 MGI
acts upstream of apoptotic process IMP
IMP: 通过突变表型推断
18003640 MGI
acts upstream of or within camera-type eye development IMP
IMP: 通过突变表型推断
15105374 MGI
acts upstream of or within cell fate specification IMP
IMP: 通过突变表型推断
18590716 MGI
acts upstream of or within dorsal/ventral neural tube patterning IDA
IDA: 通过直接分析推断
18590716 MGI
acts upstream of or within dorsal/ventral neural tube patterning IGI
IGI: 通过遗传相互作用推断
18590716 MGI
acts upstream of or within dorsal/ventral neural tube patterning IMP
IMP: 通过突变表型推断
18003640 MGI
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: 通过突变表型推断
15105374 MGI
acts upstream of or within multicellular organism growth IGI
IGI: 通过遗传相互作用推断
18590716 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
18003640 MGI
acts upstream of or within neural tube development IMP
IMP: 通过突变表型推断
18590716 MGI
acts upstream of or within neuron fate specification IMP
IMP: 通过突变表型推断
15105374 MGI
acts upstream of or within positive regulation of BMP signaling pathway IMP
IMP: 通过突变表型推断
18590716 MGI
acts upstream of or within protein folding IMP
IMP: 通过突变表型推断
29916806 MGI
acts upstream of or within regulation of BMP signaling pathway IGI
IGI: 通过遗传相互作用推断
18590716 MGI
acts upstream of or within regulation of gene expression IGI
IGI: 通过遗传相互作用推断
18590716 MGI
acts upstream of or within smoothened signaling pathway IGI
IGI: 通过遗传相互作用推断
15105374 MGI
acts upstream of or within smoothened signaling pathway IMP
IMP: 通过突变表型推断
15105374 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
15105374 MGI
located in mitochondrial envelope IDA
IDA: 通过直接分析推断
15105374 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase FKBP8

38 kDa FK506-binding protein

38 kDa FKBP

FK506-binding protein 38

PPIase FKBP8

rotamase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04968 FKBP8 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20408 Fkbp8 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26917 Fkbp8 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fkbp8 NCBI NCBI:23770
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z