2. Gene
  3. Fzd6 - frizzled class receptor 6 Gene

Fzd6 - frizzled class receptor 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fz6

基因 ID: 14368 | 基因类型: protein coding

关于 Fzd6

功能概要

Enables Wnt-protein binding activity. Acts upstream of or within several processes, including cell proliferation in midbrain; embryonic morphogenesis; and establishment of body hair planar orientation. Located in apical plasma membrane; apicolateral plasma membrane; and endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 1. Orthologous to human FZD6 (Frizzled class receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Fzd6 基因产物(4)

mRNA Protein Name
NM_001162494.1 NP_001155966.1 frizzled-6 isoform 1 precursor
NM_001411226.1 NP_001398155.1 frizzled-6 isoform 1 precursor
NM_001411227.1 NP_001398156.1 frizzled-6 isoform 2 precursor
NM_008056.4 NP_032082.3 frizzled-6 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt-protein binding IPI
IPI: 通过物理相互作用推断
15265686 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18606138 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Wnt signaling pathway, planar cell polarity pathway IDA
IDA: 通过直接分析推断
18606138 MGI
acts upstream of or within cell proliferation in midbrain IGI
IGI: 通过遗传相互作用推断
19842188 MGI
acts upstream of or within embryonic nail plate morphogenesis IMP
IMP: 通过突变表型推断
23439395 MGI
acts upstream of or within establishment of body hair planar orientation IGI
IGI: 通过遗传相互作用推断
26418459 MGI
acts upstream of or within establishment of planar polarity IGI
IGI: 通过遗传相互作用推断
16495441 MGI
acts upstream of or within hair follicle development IMP
IMP: 通过突变表型推断
15169958 MGI
acts upstream of or within inner ear morphogenesis IGI
IGI: 通过遗传相互作用推断
16495441 MGI
acts upstream of or within midbrain development IGI
IGI: 通过遗传相互作用推断
19842188 MGI
acts upstream of or within neural tube closure IGI
IGI: 通过遗传相互作用推断
16495441 MGI
acts upstream of or within platelet activation IMP
IMP: 通过突变表型推断
19901330 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
16495441 MGI
located in apical plasma membrane IDA
IDA: 通过直接分析推断
25393619 MGI
located in apicolateral plasma membrane IDA
IDA: 通过直接分析推断
17376975 MGI
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
31073040 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
31073040 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

frizzled-6

frizzled homolog 6

fz-6

mFz6

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05182 FZD6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19132 Fzd6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25622 Fzd6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fzd6 NCBI NCBI:8323
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