2. Gene
  3. Slc37a4 - solute carrier family 37 (glucose-6-phosphate transporter), member 4 Gene

Slc37a4 - solute carrier family 37 (glucose-6-phosphate transporter), member 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: G6PT; G6pt1; mG6PT; GSD-1b; 100043178

基因 ID: 14385 | 基因类型: protein coding

关于 Slc37a4

功能概要

Predicted to enable glucose 6-phosphate:inorganic phosphate antiporter activity and glucose-6-phosphate transmembrane transporter activity. Acts upstream of or within several processes, including Cholesterol homeostasis; glucose-6-phosphate transport; and hemopoiesis. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; genitourinary system; liver; nervous system; and spleen. Used to study glycogen storage disease I. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human SLC37A4 (solute carrier family 37 member 4). [provided by Alliance of Genome Resources, Apr 2022]

Slc37a4 基因产物(12)

mRNA Protein Name
NM_001293630.2 NP_001280559.1 glucose-6-phosphate exchanger SLC37A4 isoform b
NM_001293631.2 NP_001280560.1 glucose-6-phosphate exchanger SLC37A4 isoform b
NM_001357729.2 NP_001344658.1 glucose-6-phosphate exchanger SLC37A4 isoform a
NM_001357730.2 NP_001344659.1 glucose-6-phosphate exchanger SLC37A4 isoform a
NM_001378829.1 NP_001365758.1 glucose-6-phosphate exchanger SLC37A4 isoform a
NM_001378830.1 NP_001365759.1 glucose-6-phosphate exchanger SLC37A4 isoform b
NM_001378831.1 NP_001365760.1 glucose-6-phosphate exchanger SLC37A4 isoform c precursor
NM_001378832.1 NP_001365761.1 glucose-6-phosphate exchanger SLC37A4 isoform c precursor
NM_001378833.1 NP_001365762.1 glucose-6-phosphate exchanger SLC37A4 isoform c precursor
NM_001378834.1 NP_001365763.1 glucose-6-phosphate exchanger SLC37A4 isoform d precursor
NM_001411170.1 NP_001398099.1 glucose-6-phosphate exchanger SLC37A4 isoform d precursor
NM_008063.3 NP_032089.2 glucose-6-phosphate exchanger SLC37A4 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glucose 6-phosphate:phosphate antiporter activity IGI
IGI: 通过遗传相互作用推断
17006547 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of chemokine production IMP
IMP: 通过突变表型推断
16891306 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
16891306 MGI
acts upstream of or within cytokine production IMP
IMP: 通过突变表型推断
12925567 MGI
involved in gluconeogenesis IDA
IDA: 通过直接分析推断
28973635 MGI
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
12925567 MGI
acts upstream of or within glucose-6-phosphate transport IDA
IDA: 通过直接分析推断
11121425 MGI
acts upstream of or within glucose-6-phosphate transport IGI
IGI: 通过遗传相互作用推断
15661744 MGI
acts upstream of or within glucose-6-phosphate transport IMP
IMP: 通过突变表型推断
15661744 MGI
acts upstream of or within glycogen metabolic process IMP
IMP: 通过突变表型推断
12925567 MGI
acts upstream of or within intracellular calcium ion homeostasis IMP
IMP: 通过突变表型推断
12925567 MGI
acts upstream of or within lactate metabolic process IMP
IMP: 通过突变表型推断
16891306 MGI
acts upstream of or within myeloid progenitor cell differentiation IMP
IMP: 通过突变表型推断
16891306 MGI
acts upstream of or within negative regulation of chemokine production IMP
IMP: 通过突变表型推断
16891306 MGI
acts upstream of or within neutrophil chemotaxis IMP
IMP: 通过突变表型推断
16891306 MGI
acts upstream of or within neutrophil homeostasis IMP
IMP: 通过突变表型推断
16891306 MGI
acts upstream of or within positive regulation of catalytic activity IMP
IMP: 通过突变表型推断
17588937 MGI
acts upstream of or within post-embryonic hemopoiesis IMP
IMP: 通过突变表型推断
12925567 MGI
acts upstream of or within respiratory burst IMP
IMP: 通过突变表型推断
16891306 MGI
acts upstream of or within steroid metabolic process IMP
IMP: 通过突变表型推断
17588937 MGI
acts upstream of or within triglyceride metabolic process IMP
IMP: 通过突变表型推断
12925567 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in endoplasmic reticulum membrane IGI
IGI: 通过遗传相互作用推断
17006547 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glucose-6-phosphate exchanger SLC37A4

glucose 6-phosphate transporter

glucose-6-phosphatase, transport protein 1

solute carrier family 37 (glycerol-6-phosphate transporter), member 4

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13216 SLC37A4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21257 Slc37a4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27776 Slc37a4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc37a4 NCBI NCBI:2542
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