2. Gene
  3. Gabra1 - gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 Gene

Gabra1 - gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gabra-1; GABAA-alpha1; GABAAR-alpha1

基因 ID: 14394 | 基因类型: protein coding

关于 Gabra1

功能概要

Enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Contributes to GABA-gated chloride ion channel activity. Involved in inhibitory synapse assembly and regulation of postsynaptic membrane potential. Located in GABA-ergic synapse and plasma membrane. Is expressed in alimentary system; central nervous system; and eye. Used to study idiopathic generalized epilepsy. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 19 and idiopathic generalized epilepsy 13. Orthologous to human GABRA1 (gamma-aminobutyric acid type A receptor subunit alpha1). [provided by Alliance of Genome Resources, Apr 2022]

Gabra1 基因产物(2)

mRNA Protein Name
NM_001359035.1 NP_001345964.1 gamma-aminobutyric acid receptor subunit alpha-1 precursor
NM_010250.5 NP_034380.1 gamma-aminobutyric acid receptor subunit alpha-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to GABA-gated chloride ion channel activity IDA
IDA: 通过直接分析推断
27129275 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12574411 MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential EXP
EXP: 通过实验结果推断
12466441 MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: 通过直接分析推断
12466441 MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IMP
IMP: 通过突变表型推断
12466441 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in inhibitory synapse assembly IDA
IDA: 通过直接分析推断
27129275 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse EXP
EXP: 通过实验结果推断
12466441 MGI
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
12466441 MGI
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
12466441 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
25579817 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

gamma-aminobutyric acid receptor subunit alpha-1

GABA(A) receptor subunit alpha-1

GABAA alpha 1

GABAAR alpha1

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05209 GABRA1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gabra1 NCBI NCBI:2554
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