2. Gene
  3. Gabrb2 - gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 Gene

Gabrb2 - gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gabrab2; Gabrb-2; C030002O17Rik; C030021G16Rik

基因 ID: 14401 | 基因类型: protein coding

关于 Gabrb2

功能概要

Enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Contributes to GABA-gated chloride ion channel activity. Involved in several processes, including inner ear development; nervous system development; and sensory perception of sound. Located in plasma membrane. Is active in GABA-ergic synapse. Is integral component of postsynaptic specialization membrane. Is expressed in several structures, including alimentary system; heart; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autistic disorder and developmental and epileptic encephalopathy 92. Orthologous to human GABRB2 (gamma-aminobutyric acid type A receptor subunit beta2). [provided by Alliance of Genome Resources, Apr 2022]

Gabrb2 基因产物(5)

mRNA Protein Name
NM_001347314.3 NP_001334243.1 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor
NM_001362646.2 NP_001349575.1 gamma-aminobutyric acid receptor subunit beta-2 isoform 2 precursor
NM_001362647.2 NP_001349576.1 gamma-aminobutyric acid receptor subunit beta-2 isoform 2 precursor
NM_001362649.2 NP_001349578.1 gamma-aminobutyric acid receptor subunit beta-2 isoform 3
NM_008070.5 NP_032096.1 gamma-aminobutyric acid receptor subunit beta-2 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to GABA-gated chloride ion channel activity IDA
IDA: 通过直接分析推断
27129275 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12574411 MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: 通过直接分析推断
26179122 MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IMP
IMP: 通过突变表型推断
26179122 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cochlea development IMP
IMP: 通过突变表型推断
17021187 MGI
involved in inhibitory synapse assembly IDA
IDA: 通过直接分析推断
27129275 MGI
involved in inner ear receptor cell development IMP
IMP: 通过突变表型推断
17021187 MGI
involved in innervation IMP
IMP: 通过突变表型推断
17021187 MGI
involved in neuron development IMP
IMP: 通过突变表型推断
17021187 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
26179122 MGI
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
26179122 MGI
is active in postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
26297893 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

gamma-aminobutyric acid receptor subunit beta-2

GABA(A) receptor subunit beta-2

gamma-aminobutyric acid A receptor, subunit beta 2

gamma-aminobutyric acid receptor beta-2 subunit

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05216 GABRB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21133 Gabrb2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27651 Gabrb2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gabrb2 NCBI NCBI:2561
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