2. Gene
  3. Gata6 - GATA binding protein 6 Gene

Gata6 - GATA binding protein 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: GATA-6

基因 ID: 14465 | 基因类型: protein coding

关于 Gata6

功能概要

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in gene expression; heart contraction; and sinoatrial node development. Acts upstream of or within several processes, including animal organ development; cardiac muscle hypertrophy in response to stress; and endodermal cell fate determination. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and heart. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); congenital heart disease (multiple); and pancreatic hypoplasia-diabetes-congenital heart disease syndrome. Orthologous to human GATA6 (GATA binding protein 6). [provided by Alliance of Genome Resources, Apr 2022]

Gata6 基因产物(1)

mRNA Protein Name
NM_010258.3 NP_034388.2 transcription factor GATA-6
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
11733512 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
11914369 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
8660897 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15987774 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
16293227 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
16199866 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11724781 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11914369 MGI
enables transcription coactivator binding IPI
IPI: 通过物理相互作用推断
11724781 MGI
enables transcription factor binding IPI
IPI: 通过物理相互作用推断
16887115 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within animal organ formation IMP
IMP: 通过突变表型推断
16887115 MGI
acts upstream of or within cardiac muscle cell differentiation IGI
IGI: 通过遗传相互作用推断
18400219 MGI
acts upstream of or within cardiac muscle cell differentiation IMP
IMP: 通过突变表型推断
18400219 MGI
acts upstream of cardiac muscle cell proliferation IGI
IGI: 通过遗传相互作用推断
19084512 MGI
acts upstream of or within cardiac muscle hypertrophy in response to stress IMP
IMP: 通过突变表型推断
20705924 MGI
acts upstream of or within cardiac muscle tissue development IGI
IGI: 通过遗传相互作用推断
20705924 MGI
acts upstream of or within cellular response to BMP stimulus IDA
IDA: 通过直接分析推断
20501701 MGI
acts upstream of or within cellular response to gonadotropin stimulus IDA
IDA: 通过直接分析推断
9231805 MGI
acts upstream of or within club cell differentiation IGI
IGI: 通过遗传相互作用推断
17164424 MGI
acts upstream of or within endodermal cell differentiation IMP
IMP: 通过突变表型推断
9832509 MGI
acts upstream of or within endodermal cell fate determination IDA
IDA: 通过直接分析推断
20308546 MGI
acts upstream of or within epithelial cell differentiation IMP
IMP: 通过突变表型推断
16887115 MGI
involved in gene expression IMP
IMP: 通过突变表型推断
33443158 MGI
involved in heart contraction IMP
IMP: 通过突变表型推断
33443158 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
9832509 MGI
acts upstream of or within liver development IMP
IMP: 通过突变表型推断
15767668 MGI
acts upstream of or within lung saccule development IGI
IGI: 通过遗传相互作用推断
17164424 MGI
acts upstream of or within pancreas development IMP
IMP: 通过突变表型推断
16887115 MGI
acts upstream of or within pancreatic A cell differentiation IMP
IMP: 通过突变表型推断
16887115 MGI
acts upstream of or within phospholipid metabolic process IGI
IGI: 通过遗传相互作用推断
17164424 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
8660897 MGI
acts upstream of or within positive regulation of cardiac muscle cell proliferation IGI
IGI: 通过遗传相互作用推断
19084512 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
8660897 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16510470 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
9832509 MGI
acts upstream of or within regulation of gene expression IGI
IGI: 通过遗传相互作用推断
18400219 MGI
acts upstream of or within response to estrogen IDA
IDA: 通过直接分析推断
9231805 MGI
involved in sinoatrial node development IMP
IMP: 通过突变表型推断
33443158 MGI
acts upstream of or within stem cell differentiation IGI
IGI: 通过遗传相互作用推断
18400219 MGI
acts upstream of or within stem cell differentiation IMP
IMP: 通过突变表型推断
18400219 MGI
acts upstream of or within tube morphogenesis IGI
IGI: 通过遗传相互作用推断
18400219 MGI
acts upstream of or within type B pancreatic cell differentiation IMP
IMP: 通过突变表型推断
16887115 MGI
acts upstream of or within type II pneumocyte differentiation IGI
IGI: 通过遗传相互作用推断
17164424 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12130579 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
17164424 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor GATA-6

GATA-binding factor 6

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05294 GATA6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17911 Gata6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24380 Gata6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gata6 NCBI NCBI:2627
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z