1. Gene
  2. Gdf9 - growth differentiation factor 9 Gene

Gdf9 - growth differentiation factor 9 Gene

种属: Mus musculus

同用名: Gdf-9

基因 ID: 14566 | 基因类型: protein coding

关于 Gdf9

功能概要

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of Smad Family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates ovarian function. Female mice that are homozygous null for this gene are sterile with impaired folliculogenesis. [provided by RefSeq, Jul 2016]

Gdf9 基因产物(1)

mRNA Protein Name
NM_008110.2 NP_032136.2 growth/differentiation factor 9 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cell growth IMP
IMP: 通过突变表型推断
17641088 MGI
acts upstream of or within negative regulation of cell growth IMP
IMP: 通过突变表型推断
17641088 MGI
acts upstream of or within oocyte growth IMP
IMP: 通过突变表型推断
17641088 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
19480014 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

growth/differentiation factor 9

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gdf9 NCBI NCBI:2661