2. Gene
  3. Ghrh - growth hormone releasing hormone Gene

Ghrh - growth hormone releasing hormone Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: GRF; Ghrf

基因 ID: 14601 | 基因类型: protein coding

关于 Ghrh

功能概要

This gene encodes a hormone that has stimulatory effects on pituitary growth hormone synthesis and release, and somatotrope expansion. The encoded preproprotein undergoes proteolytic processing to generate the mature peptide that is secreted by hypothalamus. Mice lacking the encoded protein are deficient in the growth hormone, live longer and exhibit growth retardation, enhanced Insulin sensitivity and increased xenobiotic metabolism. [provided by RefSeq, Jul 2016]

Ghrh 基因产物(2)

mRNA Protein Name
NM_001329683.1 NP_001316612.1 somatoliberin preproprotein
NM_010285.3 NP_034415.1 somatoliberin preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth hormone-releasing hormone receptor binding IPI
IPI: 通过物理相互作用推断
11773624 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10537133 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adenohypophysis development IMP
IMP: 通过突变表型推断
15985453 MGI
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
10537133 MGI
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
1334535 MGI
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
11773624 MGI
acts upstream of or within growth hormone secretion IDA
IDA: 通过直接分析推断
15070777 MGI
acts upstream of or within growth hormone secretion IMP
IMP: 通过突变表型推断
9348175 MGI
acts upstream of hormone secretion IMP
IMP: 通过突变表型推断
15985453 MGI
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
11773624 MGI
acts upstream of or within positive regulation of hormone secretion IMP
IMP: 通过突变表型推断
9348175 MGI
acts upstream of or within positive regulation of multicellular organism growth IGI
IGI: 通过遗传相互作用推断
16246898 MGI
acts upstream of or within positive regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
15985453 MGI
acts upstream of or within response to food IDA
IDA: 通过直接分析推断
16513828 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
7867561 MGI
located in terminal bouton IDA
IDA: 通过直接分析推断
7694848 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

somatoliberin

growth hormone-releasing factor

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P3304 MR 409 Activator 99.51% 否
HY-P0089A Human growth hormone-releasing factor TFA 99.66% 否
HY-P3397A JV-1-36 acetate Antagonist 99.93% 否
HY-P0089 Human growth hormone-releasing factor / 否
HY-P3397 JV-1-36 Antagonist / 否
HY-P3594 [His1,Nle27] GHRF (1-32), amide, human / 否
HY-P3595 GHRF, porcine / 否
HY-RS05413 GHRH Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16752 Ghrh Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23191 Ghrh Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ghrh NCBI NCBI:2691
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