2. Gene
  3. Ghrhr - growth hormone releasing hormone receptor Gene

Ghrhr - growth hormone releasing hormone receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: lit; Ghrfr; little

基因 ID: 14602 | 基因类型: protein coding

关于 Ghrhr

功能概要

Enables growth hormone-releasing hormone receptor activity and peptide hormone binding activity. Involved in positive regulation of cell population proliferation. Acts upstream of or within several processes, including gland development; positive regulation of growth hormone secretion; and regulation of signal transduction. Located in plasma membrane. Is integral component of membrane. Is expressed in alimentary system; brain; metanephros; and spinal cord. Human ortholog(s) of this gene implicated in isolated growth hormone deficiency. Orthologous to human GHRHR (growth hormone releasing hormone receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ghrhr 基因产物(1)

mRNA Protein Name
NM_001003685.3 NP_001003685.2 growth hormone-releasing hormone receptor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth hormone-releasing hormone receptor activity IGI
IGI: 通过遗传相互作用推断
8391647 MGI
enables growth hormone-releasing hormone receptor activity IMP
IMP: 通过突变表型推断
10537133 MGI
enables peptide hormone binding IPI
IPI: 通过物理相互作用推断
11773624 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10537133 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adenohypophysis development IMP
IMP: 通过突变表型推断
1270792 MGI
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
1334535 MGI
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
3008329 MGI
acts upstream of or within cell maturation IMP
IMP: 通过突变表型推断
2980124 MGI
acts upstream of or within cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
16513828 MGI
acts upstream of or within determination of adult lifespan IMP
IMP: 通过突变表型推断
11371619 MGI
acts upstream of establishment of localization in cell IMP
IMP: 通过突变表型推断
3008329 MGI
acts upstream of growth hormone secretion IMP
IMP: 通过突变表型推断
3008329 MGI
acts upstream of or within hormone metabolic process IMP
IMP: 通过突变表型推断
1270792 MGI
acts upstream of hormone secretion IMP
IMP: 通过突变表型推断
7679139 MGI
acts upstream of or within lactation IMP
IMP: 通过突变表型推断
1270792 MGI
acts upstream of or within mammary gland development IMP
IMP: 通过突变表型推断
15059953 MGI
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
11773624 MGI
acts upstream of or within positive regulation of growth hormone secretion IMP
IMP: 通过突变表型推断
978118 MGI
acts upstream of or within positive regulation of hormone secretion IMP
IMP: 通过突变表型推断
7679139 MGI
acts upstream of or within positive regulation of multicellular organism growth IGI
IGI: 通过遗传相互作用推断
15690087 MGI
acts upstream of or within positive regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
1270792 MGI
acts upstream of or within regulation of insulin-like growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
7390396 MGI
acts upstream of or within regulation of intracellular steroid hormone receptor signaling pathway IMP
IMP: 通过突变表型推断
10459853 MGI
acts upstream of or within regulation of protein metabolic process IGI
IGI: 通过遗传相互作用推断
7510770 MGI
acts upstream of or within somatotropin secreting cell development IMP
IMP: 通过突变表型推断
6116352 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
10537133 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10537133 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

growth hormone-releasing hormone receptor

GHRH receptor

GRF receptor

GRFR

growth hormone-releasing factor receptor

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P0089A Human growth hormone-releasing factor TFA 99.66% 否
HY-P0089 Human growth hormone-releasing factor / 否
HY-P3594 [His1,Nle27] GHRF (1-32), amide, human / 否
HY-P3595 GHRF, porcine / 否
HY-RS05414 GHRHR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19006 Ghrhr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25495 Ghrhr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ghrhr NCBI NCBI:2692
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