2. Gene
  3. CSRP1 - cysteine and glycine rich protein 1 Gene

CSRP1 - cysteine and glycine rich protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：富半胱氨酸和甘氨酸的蛋白质 1

种属: Homo sapiens

同用名: CRP; CRP1; CSRP; CYRP; D1S181E; HEL-141; HEL-S-286

基因 ID: 1465 | 基因类型: protein coding

关于 CSRP1

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:201,483,530-201,507,123 (from NCBI)

This gene has 19 transcripts (splice variants), 261 orthologues and 2 paralogues. Broad expression in prostate (RPKM 425.1), endometrium (RPKM 406.6) and 22 other tissues.

功能概要

该基因编码富含半胱氨酸蛋白 (CSRP) 家族的成员。该基因家族包括一组 LIM 结构域蛋白，它们可能参与对发育和细胞分化很重要的调节过程。在该基因产物中发现的 LIM/双锌指基序出现在对基因调控、细胞生长和体细胞分化具有关键功能的蛋白质中。已经描述了选择性剪接的转录物变体。[RefSeq 提供，2010 年 8 月]

This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]

CSRP1 基因产物(4)

mRNA Protein Name
NM_001193570.2 NP_001180499.1 cysteine and glycine-rich protein 1 isoform 3
NM_001193571.2 NP_001180500.1 cysteine and glycine-rich protein 1 isoform 1
NM_001193572.2 NP_001180501.1 cysteine and glycine-rich protein 1 isoform 1
NM_004078.3 NP_004069.1 cysteine and glycine-rich protein 1 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
26924529 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CSRP1 蛋白结构

LIM

LIM: LIM domain (10 - 65)

LIM

LIM: LIM domain (119 - 175)

  • 0
  • 100
  • 193 a.a.
蛋白主名 其他名称

cysteine and glycine-rich protein 1

LIM-domain protein

CSRP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CSRP1 P21291 CA9 Homo sapiens Q16790
Validated Y2H
32296183
种属内
CSRP1 P21291 CA9 Homo sapiens Q16790
Y2H Array
32296183
种属内
CSRP1 P21291 CA9 Homo sapiens Q16790
Y2H Prey Pooling
32296183
种属内
CSRP1 P21291 REEP1 Homo sapiens Q9H902
Y2H Prey Pooling
32296183
种属内
CSRP1 P21291 REEP1 Homo sapiens Q9H902
Validated Y2H
32296183
种属内
CSRP1 P21291 REEP1 Homo sapiens Q9H902
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CSRP1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76298 CSRP1 Protein, Human (His) P21291 (M1-E193) ≥95%

关联疾病

疾病名称 别名
Endocardial Fibroelastosis

Endomyocardial Fibroelastosis

Elastomyofibrosis

EFE

Efe - [Endocardial Fibroelastosis]

Primary Endocardial Fibroelastosis

Fibroelastosis Cordis

Fetal Endocarditis

Fibroelastosis

Congenital Endocardial Fibroelastosis

Congenital Valvular Endocarditis
Mixed Hepatoblastoma

Mixed Epithelial And Mesenchymal Hepatoblastoma
Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy

Primary Dilated Cardiomyopathy

Idiopathic Dilated Cardiomyopathy

Congestive Cardiomyopathy

Idiopathic Dilation Cardiomyopathy

Primary Familial Dilated Cardiomyopathy

Cardiomyopathy, Dilated

DCM

Cardiomyopathy, Familial Dilated

Dilated Cardiomyopathy, Familial

Hypokinetic Dilated Cardiomyopathy, Familial

Familial Idiopathic Cardiomyopathy

Fdc

Cardiomyopathy, Familial Idiopathic

Idiopathic Cardiomegaly

Dilated Congestive Cardiomyopathy

Chronic Dilated Cardiomyopathy

Ccm - [Congestive Cardiomyopathy]

Cocm - [Congestive Cardiomyopathy]

Dcm - [Dilated Cardiomyopathy]

Dilated-Hypokinetic Cardiomyopathy

Congestive Idiopathic Cardiomyopathy

Primary Idiopathic Dilated Cardiomyopathy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03258 CSRP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18515 Csrp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24997 Csrp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CSRP1 VGNC VGNC:71527
Felis catus CSRP1 VGNC VGNC:61233
Canis familiaris CSRP1 VGNC VGNC:39675
Mus musculus CSRP1 MGD MGI:88549
Bos taurus CSRP1 VGNC VGNC:27773
Rattus norvegicus CSRP1 RGD RGD:62053
Others CSRP1 NCBI
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