2. Gene
  3. Gnal - guanine nucleotide binding protein, alpha stimulating, olfactory type Gene

Gnal - guanine nucleotide binding protein, alpha stimulating, olfactory type Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Golf; Hg1o; Gna10; Galphaolf; 2610011C15Rik; 9630020G10Rik

基因 ID: 14680 | 基因类型: protein coding

关于 Gnal

功能概要

Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Acts upstream of or within several processes, including activation of Adenylate Cyclase activity; adenylate cyclase-activating Dopamine Receptor signaling pathway; and response to caffeine. Predicted to be part of heterotrimeric G-protein complex. Is expressed in nervous system; sensory organ; and spleen. Human ortholog(s) of this gene implicated in dystonia 25. Orthologous to human GNAL (G protein subunit alpha L). [provided by Alliance of Genome Resources, Apr 2022]

Gnal 基因产物(2)

mRNA Protein Name
NM_010307.3 NP_034437.1 guanine nucleotide-binding protein G(olf) subunit alpha isoform 1
NM_177137.5 NP_796111.2 guanine nucleotide-binding protein G(olf) subunit alpha isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein activity IDA
IDA: 通过直接分析推断
21467038 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within activation of adenylate cyclase activity IDA
IDA: 通过直接分析推断
12488442 MGI
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
2499043 MGI
acts upstream of or within adenylate cyclase-activating dopamine receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
17194762 MGI
acts upstream of or within response to amphetamine IMP
IMP: 通过突变表型推断
11404425 MGI
acts upstream of or within response to caffeine IMP
IMP: 通过突变表型推断
11404425 MGI
acts upstream of or within sensory perception of smell IMP
IMP: 通过突变表型推断
9459443 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

guanine nucleotide-binding protein G(olf) subunit alpha

G alpha 10

adenylate cyclase-stimulating G alpha protein, olfactory type

guanine nucleotide binding protein, alpha 10

heterotrimeric guanine nucleotide-binding protein 1o

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05537 GNAL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17331 Gnal Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23786 Gnal Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gnal NCBI NCBI:2774
Macaca fascicularis Gnal NCBI NCBI:102137826
Rattus norvegicus Gnal NCBI NCBI:24611
Macaca mulatta Gnal NCBI NCBI:114673806
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