SLC47A2 - solute carrier family 47 member 2 Gene

中文名称：溶质载体家族 47 成员 2

种属: Homo sapiens

同用名: MATE2; MATE2K; MATE2-B; MATE2-K

关于 SLC47A2

功能概要

该基因编码的蛋白质属于转运蛋白家族，参与通过尿液和胆汁排泄内源性和外源性有毒电解质。该转运蛋白家族与负责耐药性的细菌 MATE (多药和毒素排出) 蛋白家族具有同源性。该基因是位于 17 号染色体上彼此靠近的 MATE 转运蛋白家族的两个成员之一。已经为该基因鉴定了编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the Bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each Other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]