2. Gene
  3. Gnaq - guanine nucleotide binding protein, alpha q polypeptide Gene

Gnaq - guanine nucleotide binding protein, alpha q polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gq; GqI; Dsk1; Dsk10; Galphaq; 1110005L02Rik; 6230401I02Rik

基因 ID: 14682 | 基因类型: protein coding

关于 Gnaq

功能概要

Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GTPase activator activity; and alkylglycerophosphoethanolamine phosphodiesterase activity. Involved in several processes, including cranial skeletal system development; Endothelin Receptor signaling pathway; and multicellular organism aging. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; maternal behavior; and neuron development. Located in cell body; dendrite; and membrane. Is expressed in several structures, including central nervous system; gonad; heart; intestine smooth muscle circular layer; and retina. Used to study congestive heart failure and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome; congestive heart failure; and familial multiple nevi flammei. Orthologous to human GNAQ (G protein subunit alpha q). [provided by Alliance of Genome Resources, Apr 2022]

Gnaq 基因产物(1)

mRNA Protein Name
NM_008139.6 NP_032165.3 guanine nucleotide-binding protein G(q) subunit alpha
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein activity IDA
IDA: 通过直接分析推断
20966218 MGI
enables G protein activity IMP
IMP: 通过突变表型推断
26075576 MGI
enables enzyme regulator activity IDA
IDA: 通过直接分析推断
37991948 MGI
enables enzyme regulator activity IMP
IMP: 通过突变表型推断
26075576 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9016340 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
9687499 MGI
acts upstream of or within action potential IMP
IMP: 通过突变表型推断
10818132 MGI
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
10481072 MGI
involved in cranial skeletal system development IGI
IGI: 通过遗传相互作用推断
18199583 MGI
acts upstream of or within developmental pigmentation IMP
IMP: 通过突变表型推断
15322542 MGI
acts upstream of or within embryonic digit morphogenesis IGI
IGI: 通过遗传相互作用推断
12077299 MGI
involved in endothelin receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
18199583 MGI
acts upstream of or within forebrain neuron development IMP
IMP: 通过突变表型推断
15340067 MGI
acts upstream of or within glutamate receptor signaling pathway IMP
IMP: 通过突变表型推断
11438569 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
9687499 MGI
involved in ion channel modulating, G protein-coupled receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
20440069 MGI
involved in ligand-gated ion channel signaling pathway IGI
IGI: 通过遗传相互作用推断
20440069 MGI
involved in ligand-gated ion channel signaling pathway IMP
IMP: 通过突变表型推断
26075576 MGI
acts upstream of or within maternal behavior IMP
IMP: 通过突变表型推断
15340067 MGI
acts upstream of or within neuron remodeling IMP
IMP: 通过突变表型推断
9391157 MGI
involved in phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
20440069 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
20966218 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
20440069 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
26075576 MGI
acts upstream of or within phospholipase C-activating dopamine receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
17194762 MGI
involved in positive regulation of insulin secretion IGI
IGI: 通过遗传相互作用推断
20440069 MGI
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
26075576 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
15340067 MGI
involved in regulation of blood pressure IGI
IGI: 通过遗传相互作用推断
26531127 MGI
acts upstream of or within regulation of melanocyte differentiation IMP
IMP: 通过突变表型推断
15322542 MGI
involved in regulation of platelet activation IMP
IMP: 通过突变表型推断
9296496 MGI
acts upstream of or within skeletal system development IMP
IMP: 通过突变表型推断
9687499 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell body IDA
IDA: 通过直接分析推断
11685543 MGI
located in dendrite IDA
IDA: 通过直接分析推断
11685543 MGI
located in membrane IDA
IDA: 通过直接分析推断
9016340 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
9765251 MGI
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
27276689 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

guanine nucleotide-binding protein G(q) subunit alpha

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05539 GNAQ Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22188 Gnaq Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28710 Gnaq Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gnaq NCBI NCBI:2776
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z