2. Gene
  3. RUNDC1 - RUN domain containing 1 Gene

RUNDC1 - RUN domain containing 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 RUN 域 1

种属: Homo sapiens

同用名: RUND1

基因 ID: 146923 | 基因类型: protein coding

关于 RUNDC1

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:42,980,565-42,995,142 (from NCBI)

This gene has 3 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in brain (RPKM 7.5), thyroid (RPKM 6.9) and 25 other tissues.

功能概要

该基因编码的蛋白质包含一个 RUN (RPIP8、UNC-14 和 NESCA) 结构域和一个卷曲螺旋结构域。编码的蛋白质可能负向调节 p53 转录活性。该基因是人类神经胶质瘤易感性的潜在候选基因。[RefSeq 提供，2017 年 5 月]

This gene encodes a protein that contains a RUN (RPIP8, UNC-14 and NESCA) domain and a coiled coil domain. The encoded protein may negatively regulate p53 transcriptional activity. This gene is a potential candidate gene for predisposition to glioma in humans. [provided by RefSeq, May 2017]

RUNDC1 基因产物(3)

mRNA Protein Name
NM_001321381.3 NP_001308310.2 RUN domain-containing protein 1 isoform 2
NM_001394222.1 NP_001381151.1 RUN domain-containing protein 1 isoform 3
NM_173079.5 NP_775102.3 RUN domain-containing protein 1 isoform 1

RUNDC1 蛋白结构

RUN

RUN: RUN domain (430 - 601)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 613 a.a.
蛋白主名 其他名称

RUN domain-containing protein 1

关联疾病

疾病名称 别名
Mitochondrial Complex Iv Deficiency, Nuclear Type 1

Cytochrome C Oxidase Deficiency

Mitochondrial Complex Iv Deficiency

Cox Deficiency

Cytochrome-C Oxidase Deficiency Disease

MC1DN4

Cytochrome-C Oxidase Deficiency

MC4DN1

Mitochondrial Complex I Deficiency, Nuclear Type 4

Complex 4 Mitochondrial Respiratory Chain Deficiency

Complex Iv Deficiency

Mitochondrial Complex 1 Deficiency, Nuclear Type 4

Nuclear Type Mitochondrial Complex I Deficiency 4

Deficiency Of Mitochondrial Respiratory Chain Complex4

MT-C4D

Complex Iv Mitochondrial Respiratory Chain Deficiency

Lethal Neonatal Cardiomyopathy Hypertrophic Due To Cytochrome C Oxidase Deficiency

Mitochondrial Complex Iv Deficiency, Nuclear, Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12347 RUNDC1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus RUNDC1 MGD MGI:2144506
Felis catus RUNDC1 VGNC VGNC:99441
Macaca mulatta RUNDC1 VGNC VGNC:77101
Bos taurus RUNDC1 VGNC VGNC:34217
Rattus norvegicus RUNDC1 RGD RGD:1307490
Canis familiaris RUNDC1 VGNC VGNC:45806
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