1. Gene
  2. Gnb5 - guanine nucleotide binding protein (G protein), beta 5 Gene

Gnb5 - guanine nucleotide binding protein (G protein), beta 5 Gene

种属: Mus musculus

同用名: GBS; flr; Hg2e; Gbeta5

基因 ID: 14697 | 基因类型: protein coding

关于 Gnb5

功能概要

Predicted to enable several functions, including G-protein gamma-subunit binding activity; GTPase activating protein binding activity; and chaperone binding activity. Predicted to contribute to GTPase activator activity. Acts upstream of or within G protein-coupled receptor signaling pathway; dark adaptation; and light adaption. Located in several cellular components, including nucleus; photoreceptor inner segment; and photoreceptor outer segment. Is active in presynapse. Is expressed in several structures, including brain; eye; genitourinary system; liver; and lung. Human ortholog(s) of this gene implicated in intellectual developmental disorder with cardiac arrhythmia. Orthologous to human GNB5 (G protein subunit beta 5). [provided by Alliance of Genome Resources, Apr 2022]

Gnb5 基因产物(2)

mRNA Protein Name
NM_010313.2 NP_034443.1 guanine nucleotide-binding protein subunit beta-5 isoform 1
NM_138719.5 NP_619733.1 guanine nucleotide-binding protein subunit beta-5 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15897264 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
15897264 MGI
acts upstream of or within dark adaptation IDA
IDA: 通过直接分析推断
23555598 MGI
acts upstream of or within light adaption IDA
IDA: 通过直接分析推断
23555598 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cell tip IDA
IDA: 通过直接分析推断
25997951 MGI
is active in dendrite IDA
IDA: 通过直接分析推断
25997951 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15897264 MGI
is active in parallel fiber to Purkinje cell synapse IDA
IDA: 通过直接分析推断
27965545 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15897264 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
21766168 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
27965545 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
21766168 MGI
is active in synapse EXP
EXP: 通过实验结果推断
34932372 MGI
is active in synapse IDA
IDA: 通过直接分析推断
34932372 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

guanine nucleotide-binding protein subunit beta-5

flail

flailer

guanine nucleotide binding protein, beta 5

heterotrimeric guanine nucleotide-binding protein 2e

hug

transducin beta chain 5

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gnb5 NCBI NCBI:10681