2. Gene
  3. Got2 - glutamatic-oxaloacetic transaminase 2, mitochondrial Gene

Got2 - glutamatic-oxaloacetic transaminase 2, mitochondrial Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Got-2; Kyat4; mAspAT; FABP-pm

基因 ID: 14719 | 基因类型: protein coding

关于 Got2

功能概要

Enables L-aspartate:2-oxoglutarate aminotransferase activity. Acts upstream of or within dicarboxylic acid metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Orthologous to human GOT2 (glutamic-oxaloacetic transaminase 2). [provided by Alliance of Genome Resources, Apr 2022]

Got2 基因产物(1)

mRNA Protein Name
NM_010325.3 NP_034455.1 aspartate aminotransferase, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-aspartate:2-oxoglutarate aminotransferase activity IDA
IDA: 通过直接分析推断
869894 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aspartate biosynthetic process IDA
IDA: 通过直接分析推断
4193185 MGI
acts upstream of or within glutamate catabolic process IDA
IDA: 通过直接分析推断
4193185 MGI
acts upstream of or within glutamate catabolic process to aspartate IDA
IDA: 通过直接分析推断
4193185 MGI
involved in malate-aspartate shuttle IMP
IMP: 通过突变表型推断
34450065 MGI
acts upstream of or within oxaloacetate metabolic process IDA
IDA: 通过直接分析推断
4193185 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in mitochondrial matrix IDA
IDA: 通过直接分析推断
4193185 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
4193185 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

aspartate aminotransferase, mitochondrial

FABP-1

FABPpm

fatty acid-binding protein

glutamate oxaloacetate transaminase 2, mitochondrial

kynurenine aminotransferase 4

kynurenine aminotransferase IV

kynurenine--oxoglutarate transaminase 4

kynurenine--oxoglutarate transaminase IV

mitochondri

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05606 GOT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17809 Got2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24277 Got2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Got2 NCBI NCBI:2806
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