2. Gene
  3. CREB3L4 - cAMP responsive element binding protein 3 like 4 Gene

CREB3L4 - cAMP responsive element binding protein 3 like 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：cAMP 反应元件结合蛋白 3 like 4

种属: Homo sapiens

同用名: JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP

基因 ID: 148327 | 基因类型: protein coding

关于 CREB3L4

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:153,967,487-153,974,359 (from NCBI)

This gene has 13 transcripts (splice variants), 195 orthologues and 9 paralogues. Broad expression in prostate (RPKM 52.3), stomach (RPKM 10.0) and 20 other tissues.

功能概要

该基因编码具有跨膜结构域的 CREB (cAMP 反应元件结合) 蛋白，将其定位于 ER 膜。所编码的蛋白质是一种包含二聚化结构域的转录激活因子，该蛋白质可能在包括蛋白质加工在内的许多加工途径中发挥作用。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2011 年 12 月]

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

CREB3L4 基因产物(5)

mRNA Protein Name
NM_001255978.2 NP_001242907.1 cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 1
NM_001255979.2 NP_001242908.1 cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 1
NM_001255980.2 NP_001242909.1 cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 2
NM_001255981.2 NP_001242910.1 cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 2
NM_130898.4 NP_570968.1 cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 1

CREB3L4 蛋白结构

bZIP_1

bZIP_1: bZIP transcription factor (215 - 273)

  • 0
  • 100
  • 200
  • 300
  • 395 a.a.
蛋白主名 其他名称

cyclic AMP-responsive element-binding protein 3-like protein 4

CREB-4

关联疾病

疾病名称 别名
Nemaline Myopathy 1

Cap Myopathy 1

NEM1

Nemaline Myopathy 1, Autosomal Dominant Or Recessive

Nemaline Myopathy, Type 1

CAPM1

Cap Disease

Cap Myopathy Tpm3-Related

Nemaline Myopathy 1 Autosomal Dominant Or Recessive

Myopathy, Nemaline, Type 1

Cap Myopathy
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Myxofibrosarcoma

Fibromyxosarcoma

Fibromyxoid Sarcoma

Myxoid Malignant Fibrous Histiocytoma

Dermatofibrosarcoma Protuberans, Myxoid
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03153 CREB3L4 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CREB3L4 RGD RGD:1359278
Canis familiaris CREB3L4 VGNC VGNC:39599
Macaca mulatta CREB3L4 VGNC VGNC:71437
Mus musculus CREB3L4 MGD MGI:1916603
Felis catus CREB3L4 VGNC VGNC:61169
Bos taurus CREB3L4 VGNC VGNC:27697
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