1. Gene
  2. PM20D1 - peptidase M20 domain containing 1 Gene

PM20D1 - peptidase M20 domain containing 1 Gene

中文名称:含肽酶 M20 域 1

种属: Homo sapiens

同用名: Cps1

基因 ID: 148811 | 基因类型: protein coding

关于 PM20D1

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:205,828,025-205,850,132 (from NCBI)

This gene has 4 transcripts (splice variants), 215 orthologues and 3 paralogues. Biased expression in pancreas (RPKM 10.8), urinary bladder (RPKM 2.6) and 3 other tissues.

功能概要

启用水解酶活性,作用于线性酰胺中的碳-氮 (但不是肽) 键。涉及多个过程,包括酰胺生物合成过程;细胞酰胺分解代谢过程;和神经元死亡的负调节。位于细胞外外泌体。 [由基因组资源联盟提供,2022 年 4 月]

Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Involved in several processes, including amide biosynthetic process; cellular amide catabolic process; and negative regulation of neuron death. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PM20D1 基因产物(1)

mRNA Protein Name
NM_152491.5 NP_689704.4 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides EXP
EXP: 通过实验结果推断
27374330 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in amide biosynthetic process IDA
IDA: 通过直接分析推断
27374330 GOA
involved in amide catabolic process IDA
IDA: 通过直接分析推断
27374330 GOA
involved in amino acid metabolic process IDA
IDA: 通过直接分析推断
27374330 GOA
involved in cellular lipid metabolic process IDA
IDA: 通过直接分析推断
27374330 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PM20D1 蛋白结构

Peptidase_M20

Peptidase_M20: Peptidase family M20/M25/M40 (121 - 488)

M20_dimer

M20_dimer: Peptidase dimerisation domain (240 - 383)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 502 a.a.
蛋白主名 其他名称

N-fatty-acyl-amino acid synthase/hydrolase PM20D1

peptidase M20 domain-containing protein 1

关联疾病

疾病名称 别名
Transient Arthritis
Norwegian Scabies

Crusted Scabies

Seven Year Itch

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PM20D1 RGD RGD:1564063
Mus musculus PM20D1 MGD MGI:2442939
Felis catus PM20D1 VGNC VGNC:64252
Bos taurus PM20D1 VGNC VGNC:33066
Canis familiaris PM20D1 VGNC VGNC:44727
Macaca mulatta PM20D1 VGNC VGNC:76118