2. Gene
  3. Hcls1 - hematopoietic cell specific Lyn substrate 1 Gene

Hcls1 - hematopoietic cell specific Lyn substrate 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HS1

基因 ID: 15163 | 基因类型: protein coding

关于 Hcls1

功能概要

Enables SH3 domain binding activity. Involved in several processes, including positive regulation of myeloid leukocyte differentiation; positive regulation of tyrosine phosphorylation of STAT protein; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in thymus primordium. Orthologous to human HCLS1 (hematopoietic cell-specific Lyn substrate 1). [provided by Alliance of Genome Resources, Apr 2022]

Hcls1 基因产物(1)

mRNA Protein Name
NM_008225.2 NP_032251.2 hematopoietic lineage cell-specific protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH3 domain binding IDA
IDA: 通过直接分析推断
9126384 MGI
enables SH3 domain binding IPI
IPI: 通过物理相互作用推断
19064729 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7506729 MGI
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
19064729 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in erythrocyte differentiation IMP
IMP: 通过突变表型推断
10713104 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
23001182 MGI
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
10713104 MGI
involved in positive regulation of granulocyte differentiation IMP
IMP: 通过突变表型推断
23001182 MGI
involved in positive regulation of macrophage differentiation IMP
IMP: 通过突变表型推断
23001182 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
23001182 MGI
involved in response to hormone IDA
IDA: 通过直接分析推断
10713104 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
10713104 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10713104 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hematopoietic lineage cell-specific protein

hematopoietic cell-specific LYN substrate 1

lckBP1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06045 HCLS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17702 Hcls1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24166 Hcls1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hcls1 NCBI NCBI:3059
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