1. Gene
  2. Foxf1 - forkhead box F1 Gene

Foxf1 - forkhead box F1 Gene

种属: Mus musculus

同用名: Hfh8; HFH-8; FREAC1; Foxf1a; Freac-1

基因 ID: 15227 | 基因类型: protein coding

关于 Foxf1

功能概要

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; chordate embryonic development; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; respiratory system; and urethra. Used to study persistent fetal circulation syndrome. Human ortholog(s) of this gene implicated in persistent fetal circulation syndrome. Orthologous to human FOXF1 (forkhead box F1). [provided by Alliance of Genome Resources, Apr 2022]

Foxf1 基因产物(1)

mRNA Protein Name
NM_010426.3 NP_034556.2 forkhead box protein F1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15987774 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
7958446 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within animal organ morphogenesis IMP
IMP: 通过突变表型推断
11809759 MGI
acts upstream of or within cell-cell adhesion IMP
IMP: 通过突变表型推断
11124112 MGI
acts upstream of or within cellular response to cytokine stimulus IDA
IDA: 通过直接分析推断
9486531 MGI
acts upstream of or within cellular response to organic cyclic compound IMP
IMP: 通过突变表型推断
18421012 MGI
acts upstream of or within detection of wounding IMP
IMP: 通过突变表型推断
12500195 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within embryonic digestive tract development IGI
IGI: 通过遗传相互作用推断
16439479 MGI
acts upstream of or within embryonic foregut morphogenesis IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within epithelial cell differentiation involved in mammary gland alveolus development IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within epithelial tube branching involved in lung morphogenesis IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within establishment of epithelial cell apical/basal polarity IGI
IGI: 通过遗传相互作用推断
16439479 MGI
acts upstream of or within extracellular matrix organization IGI
IGI: 通过遗传相互作用推断
16439479 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
11124112 MGI
acts upstream of or within lateral mesodermal cell differentiation IMP
IMP: 通过突变表型推断
11124112 MGI
acts upstream of or within lung alveolus development IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
11437453 MGI
acts upstream of or within lung lobe morphogenesis IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within lung morphogenesis IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within mesenchyme migration IMP
IMP: 通过突变表型推断
17261592 MGI
acts upstream of or within mesoderm development IGI
IGI: 通过遗传相互作用推断
11124112 MGI
acts upstream of or within mesoderm development IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within mesodermal cell differentiation IGI
IGI: 通过遗传相互作用推断
17881493 MGI
acts upstream of or within mesodermal cell differentiation IMP
IMP: 通过突变表型推断
17881493 MGI
acts upstream of or within negative regulation of inflammatory response IMP
IMP: 通过突变表型推断
18421012 MGI
acts upstream of or within negative regulation of mast cell degranulation IMP
IMP: 通过突变表型推断
18421012 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
11124112 MGI
acts upstream of or within positive regulation of cell migration IMP
IMP: 通过突变表型推断
17261592 MGI
acts upstream of or within positive regulation of cell-substrate adhesion IMP
IMP: 通过突变表型推断
17261592 MGI
acts upstream of or within positive regulation of mesenchymal cell proliferation IMP
IMP: 通过突变表型推断
11124112 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
7958446 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17261592 MGI
acts upstream of or within right lung morphogenesis IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within smooth muscle cell differentiation IGI
IGI: 通过遗传相互作用推断
17881493 MGI
acts upstream of or within smooth muscle cell differentiation IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within smoothened signaling pathway IDA
IDA: 通过直接分析推断
11493558 MGI
acts upstream of or within somitogenesis IMP
IMP: 通过突变表型推断
11124112 MGI
acts upstream of or within trachea development IMP
IMP: 通过突变表型推断
11493558 MGI
acts upstream of or within vasculogenesis IMP
IMP: 通过突变表型推断
11124112 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
17261592 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

forkhead box protein F1

HNF-3/forkhead homolog 8

forkhead box F1a

forkhead-related protein FKHL5

forkhead-related transcription factor 1

hepatocyte nuclear factor 3 forkhead homolog 8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Foxf1 NCBI NCBI:2294