1. Gene
  2. Foxd1 - forkhead box D1 Gene

Foxd1 - forkhead box D1 Gene

种属: Mus musculus

同用名: BF-2; Hfh10; FREAC4; Hfhbf2

基因 ID: 15229 | 基因类型: protein coding

关于 Foxd1

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including kidney development; luteinizing hormone secretion; and regulation of gene expression. Acts upstream of or within axon guidance; branching involved in ureteric bud morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; integumental system; metanephros; nervous system; and sensory organ. Orthologous to human FOXD1 (forkhead box D1). [provided by Alliance of Genome Resources, Apr 2022]

Foxd1 基因产物(1)

mRNA Protein Name
NM_008242.2 NP_032268.2 forkhead box protein D1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
13678594 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
13678594 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
13678594 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
13678594 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
15509772 MGI
acts upstream of or within branching involved in ureteric bud morphogenesis IDA
IDA: 通过直接分析推断
13678594 MGI
involved in canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
32868762 MGI
involved in dichotomous subdivision of terminal units involved in ureteric bud branching IMP
IMP: 通过突变表型推断
15634693 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
8666231 MGI
involved in luteinizing hormone secretion IMP
IMP: 通过突变表型推断
23284914 MGI
involved in metanephric capsule development IMP
IMP: 通过突变表型推断
15634693 MGI
involved in metanephric capsule specification IMP
IMP: 通过突变表型推断
15634693 MGI
involved in metanephric nephron development IMP
IMP: 通过突变表型推断
15634693 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
15634693 MGI
involved in nephrogenic mesenchyme development IMP
IMP: 通过突变表型推断
15634693 MGI
involved in pattern specification involved in metanephros development IMP
IMP: 通过突变表型推断
15634693 MGI
involved in positive regulation of BMP signaling pathway IMP
IMP: 通过突变表型推断
15634693 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
15634693 MGI
involved in positive regulation of kidney development IMP
IMP: 通过突变表型推断
15634693 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
13678594 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
13678594 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

forkhead box protein D1

FORKHEAD BOX PROTEIN D1 (FORKHEAD-RELATED PROTEIN FKHL8) (FORKHEAD-RELATED TRANSCRIPTION FACTOR 4) (FREAC-4)

FREAC-4

HFH-BF-2

HNF-3/forkhead homolog, brain factor 2

brain factor 2

forkhead-related protein FKHL8

forkhead-related transcription factor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Foxd1 NCBI NCBI:2297