2. Gene
  3. Hhip - Hedgehog-interacting protein Gene

Hhip - Hedgehog-interacting protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Hhip1

基因 ID: 15245 | 基因类型: protein coding

关于 Hhip

功能概要

Predicted to enable Hedgehog family protein binding activity and zinc ion binding activity. Involved in negative regulation of smoothened signaling pathway and skeletal system morphogenesis. Acts upstream of or within several processes, including epithelial tube branching involved in lung morphogenesis; neuroblast proliferation; and regulation of Fibroblast Growth Factor receptor signaling pathway. Located in cell surface. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; limb; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Orthologous to human HHIP (Hedgehog interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Hhip 基因产物(1)

mRNA Protein Name
NM_020259.4 NP_064655.4 hedgehog-interacting protein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10050855 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within animal organ morphogenesis IMP
IMP: 通过突变表型推断
12917290 MGI
acts upstream of or within dorsal/ventral pattern formation IGI
IGI: 通过遗传相互作用推断
15576403 MGI
acts upstream of or within epithelial tube branching involved in lung morphogenesis IMP
IMP: 通过突变表型推断
12569124 MGI
acts upstream of or within negative regulation of smoothened signaling pathway IDA
IDA: 通过直接分析推断
10050855 MGI
involved in negative regulation of smoothened signaling pathway IDA
IDA: 通过直接分析推断
15294024 MGI
acts upstream of or within negative regulation of smoothened signaling pathway IMP
IMP: 通过突变表型推断
12569124 MGI
acts upstream of or within neuroblast proliferation IGI
IGI: 通过遗传相互作用推断
15576403 MGI
acts upstream of or within regulation of fibroblast growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
12569124 MGI
acts upstream of or within signal transduction IDA
IDA: 通过直接分析推断
10050855 MGI
involved in skeletal system morphogenesis IMP
IMP: 通过突变表型推断
10050855 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
15576403 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10050855 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hedgehog-interacting protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06160 HHIP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21354 Hhip Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27873 Hhip Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hhip NCBI NCBI:64399
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