2. Gene
  3. Mnx1 - motor neuron and pancreas homeobox 1 Gene

Mnx1 - motor neuron and pancreas homeobox 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HB9; MNR2; Hlxb9

基因 ID: 15285 | 基因类型: protein coding

关于 Mnx1

功能概要

Predicted to enable sequence-specific double-stranded DNA binding activity. Acts upstream of or within several processes, including diaphragm development; endocrine pancreas development; and nervous system development. Located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; lung epithelium; and notochord. Human ortholog(s) of this gene implicated in Currarino syndrome. Orthologous to human MNX1 (motor neuron and pancreas homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Mnx1 基因产物(1)

mRNA Protein Name
NM_019944.2 NP_064328.2 motor neuron and pancreas homeobox protein 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell morphogenesis involved in neuron differentiation IMP
IMP: 通过突变表型推断
10482234 MGI
acts upstream of or within central nervous system neuron differentiation IMP
IMP: 通过突变表型推断
10482234 MGI
acts upstream of or within diaphragm development IMP
IMP: 通过突变表型推断
10482234 MGI
acts upstream of or within dorsal/ventral neural tube patterning IDA
IDA: 通过直接分析推断
18590716 MGI
acts upstream of or within endocrine pancreas development IMP
IMP: 通过突变表型推断
10471501 MGI
acts upstream of or within motor neuron axon guidance IMP
IMP: 通过突变表型推断
10482234 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18539116 MGI
acts upstream of or within nerve development IMP
IMP: 通过突变表型推断
11395002 MGI
acts upstream of or within neuron differentiation IMP
IMP: 通过突变表型推断
11395002 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
10482234 MGI
acts upstream of or within neuron projection morphogenesis IMP
IMP: 通过突变表型推断
10482234 MGI
acts upstream of or within pancreas development IMP
IMP: 通过突变表型推断
10471501 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
10482234 MGI
acts upstream of or within respiratory system development IMP
IMP: 通过突变表型推断
10482234 MGI
acts upstream of or within spinal cord motor neuron cell fate specification IMP
IMP: 通过突变表型推断
10482234 MGI
involved in spinal cord motor neuron cell fate specification IMP
IMP: 通过突变表型推断
18539116 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
18539116 MGI
located in nucleus IDA
IDA: 通过直接分析推断
17042795 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

motor neuron and pancreas homeobox protein 1

homeobox gene HB9

homeobox protein HB9

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08571 MNX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174579 Human MNX1 mRNA / 否
HY-RS20296 Mnx1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26804 Mnx1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mnx1 NCBI NCBI:3110
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