2. Gene
  3. Hmgcl - 3-hydroxy-3-methylglutaryl-Coenzyme A lyase Gene

Hmgcl - 3-hydroxy-3-methylglutaryl-Coenzyme A lyase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HL

基因 ID: 15356 | 基因类型: protein coding

关于 Hmgcl

功能概要

Predicted to enable several functions, including fatty-acyl-CoA binding activity; hydroxymethylglutaryl-CoA lyase activity; and metal ion binding activity. Acts upstream of or within mitochondrion organization. Located in mitochondrion. Is expressed in alimentary system; cranium; and liver. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Orthologous to human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase). [provided by Alliance of Genome Resources, Apr 2022]

Hmgcl 基因产物(3)

mRNA Protein Name
NM_001357529.1 NP_001344458.1 hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 2
NM_001357530.1 NP_001344459.1 hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 3
NM_008254.3 NP_032280.2 hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within embryo development IMP
IMP: 通过突变表型推断
9817922 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
9817922 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
26767982 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hydroxymethylglutaryl-CoA lyase, mitochondrial

3-hydroxy-3-methylglutarate-CoA lyase

HMG-CoA lyase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06236 HMGCL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20953 Hmgcl Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27470 Hmgcl Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hmgcl NCBI NCBI:3155
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