2. Gene
  3. Hmga1 - high mobility group AT-hook 1 Gene

Hmga1 - high mobility group AT-hook 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Hmgi; Hmgy; Hmgiy; Hmga1a; Hmga1b

基因 ID: 15361 | 基因类型: protein coding

关于 Hmga1

功能概要

This locus encodes a member of the nuclear, non-histone high mobility group protein family. This architectural transcription factor binds to A-T rich DNA sequences and participates in enhanceosome formation, chromatin remodeling and regulation of transcription. This protein functions in many cellular processes, including cell growth and differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

Hmga1 基因产物(63)

mRNA Protein Name
NM_001025427.3 NP_001020598.1 high mobility group protein HMG-I/HMG-Y isoform a
NM_001039356.2 NP_001034445.1 high mobility group protein HMG-I/HMG-Y isoform a
NM_001166535.1 NP_001160007.1 high mobility group protein HMG-I/HMG-Y isoform a
NM_001166536.1 NP_001160008.1 high mobility group protein HMG-I/HMG-Y isoform a
NM_001166537.1 NP_001160009.1 high mobility group protein HMG-I/HMG-Y isoform b
NM_001166539.1 NP_001160011.1 high mobility group protein HMG-I/HMG-Y isoform b
NM_001166540.1 NP_001160012.1 high mobility group protein HMG-I/HMG-Y isoform b
NM_001166541.1 NP_001160013.1 high mobility group protein HMG-I/HMG-Y isoform b
NM_001166542.1 NP_001160014.1 high mobility group protein HMG-I/HMG-Y isoform b
NM_001166543.1 NP_001160015.1 high mobility group protein HMG-I/HMG-Y isoform c
NM_001166544.1 NP_001160016.1 high mobility group protein HMG-I/HMG-Y isoform c
NM_001166545.1 NP_001160017.1 high mobility group protein HMG-I/HMG-Y isoform d
NM_001166546.1 NP_001160018.1 high mobility group protein HMG-I/HMG-Y isoform e
NM_001412718.1 NP_001399647.1 high mobility group protein HMG-I/HMG-Y
NM_001412721.1 NP_001399650.1 high mobility group protein HMG-I/HMG-Y
NM_001412722.1 NP_001399651.1 high mobility group protein HMG-I/HMG-Y
NM_001412723.1 NP_001399652.1 high mobility group protein HMG-I/HMG-Y
NM_001412724.1 NP_001399653.1 high mobility group protein HMG-I/HMG-Y
NM_001412726.1 NP_001399655.1 high mobility group protein HMG-I/HMG-Y
NM_001412727.1 NP_001399656.1 high mobility group protein HMG-I/HMG-Y
NM_001412728.1 NP_001399657.1 high mobility group protein HMG-I/HMG-Y
NM_001412729.1 NP_001399658.1 high mobility group protein HMG-I/HMG-Y
NM_001412730.1 NP_001399659.1 high mobility group protein HMG-I/HMG-Y
NM_001412731.1 NP_001399660.1 high mobility group protein HMG-I/HMG-Y
NM_001412732.1 NP_001399661.1 high mobility group protein HMG-I/HMG-Y
NM_001412733.1 NP_001399662.1 high mobility group protein HMG-I/HMG-Y
NM_001412740.1 NP_001399669.1 high mobility group protein HMG-I/HMG-Y
NM_001412748.1 NP_001399677.1 high mobility group protein HMG-I/HMG-Y
NM_001412749.1 NP_001399678.1 high mobility group protein HMG-I/HMG-Y
NM_001412750.1 NP_001399679.1 high mobility group protein HMG-I/HMG-Y
NM_001412751.1 NP_001399680.1 high mobility group protein HMG-I/HMG-Y
NM_001412752.1 NP_001399681.1 high mobility group protein HMG-I/HMG-Y
NM_001412754.1 NP_001399683.1 high mobility group protein HMG-I/HMG-Y
NM_001412755.1 NP_001399684.1 high mobility group protein HMG-I/HMG-Y
NM_001412764.1 NP_001399693.1 high mobility group protein HMG-I/HMG-Y
NM_001412765.1 NP_001399694.1 high mobility group protein HMG-I/HMG-Y
NM_001412766.1 NP_001399695.1 high mobility group protein HMG-I/HMG-Y
NM_001412767.1 NP_001399696.1 high mobility group protein HMG-I/HMG-Y
NM_001412768.1 NP_001399697.1 high mobility group protein HMG-I/HMG-Y
NM_001412769.1 NP_001399698.1 high mobility group protein HMG-I/HMG-Y
NM_001412770.1 NP_001399699.1 high mobility group protein HMG-I/HMG-Y
NM_001412771.1 NP_001399700.1 high mobility group protein HMG-I/HMG-Y
NM_001412772.1 NP_001399701.1 high mobility group protein HMG-I/HMG-Y
NM_001412773.1 NP_001399702.1 high mobility group protein HMG-I/HMG-Y
NM_001412783.1 NP_001399712.1 high mobility group protein HMG-I/HMG-Y
NM_001412943.1 NP_001399872.1 high mobility group protein HMG-I/HMG-Y
NM_001412944.1 NP_001399873.1 high mobility group protein HMG-I/HMG-Y
NM_001412945.1 NP_001399874.1 high mobility group protein HMG-I/HMG-Y
NM_001412949.1 NP_001399878.1 high mobility group protein HMG-I/HMG-Y
NM_001412950.1 NP_001399879.1 high mobility group protein HMG-I/HMG-Y
NM_001412951.1 NP_001399880.1 high mobility group protein HMG-I/HMG-Y
NM_001412952.1 NP_001399881.1 high mobility group protein HMG-I/HMG-Y
NM_001412953.1 NP_001399882.1 high mobility group protein HMG-I/HMG-Y
NM_001412954.1 NP_001399883.1 high mobility group protein HMG-I/HMG-Y
NM_001412955.1 NP_001399884.1 high mobility group protein HMG-I/HMG-Y
NM_001412956.1 NP_001399885.1 high mobility group protein HMG-I/HMG-Y
NM_001412957.1 NP_001399886.1 high mobility group protein HMG-I/HMG-Y
NM_001412958.1 NP_001399887.1 high mobility group protein HMG-I/HMG-Y
NM_001412959.1 NP_001399888.1 high mobility group protein HMG-I/HMG-Y
NM_001413142.1 NP_001400071.1 high mobility group protein HMG-I/HMG-Y
NM_001413143.1 NP_001400072.1 high mobility group protein HMG-I/HMG-Y
NM_001413144.1 NP_001400073.1 high mobility group protein HMG-I/HMG-Y
NM_016660.3 NP_057869.2 high mobility group protein HMG-I/HMG-Y isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables D-loop DNA binding IDA
IDA: 通过直接分析推断
15893306 MGI
enables DNA binding IDA
IDA: 通过直接分析推断
22355763 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
19389484 MGI
enables RNA polymerase II core promoter sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15713121 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
19389484 MGI
enables minor groove of adenine-thymine-rich DNA binding IDA
IDA: 通过直接分析推断
19389484 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16870469 MGI
enables transcription coactivator activity IDA
IDA: 通过直接分析推断
19389484 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within B cell differentiation IDA
IDA: 通过直接分析推断
32341372 MGI
acts upstream of or within T cell differentiation IMP
IMP: 通过突变表型推断
15713121 MGI
acts upstream of or within autophagy IDA
IDA: 通过直接分析推断
32123163 MGI
acts upstream of or within cell population proliferation IMP
IMP: 通过突变表型推断
15713121 MGI
acts upstream of or within chromatin organization IMP
IMP: 通过突变表型推断
22797695 MGI
acts upstream of or within erythrocyte differentiation IMP
IMP: 通过突变表型推断
15713121 MGI
acts upstream of or within gene expression IDA
IDA: 通过直接分析推断
22355763 MGI
acts upstream of or within gene expression IGI
IGI: 通过遗传相互作用推断
29867121 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
15713121 MGI
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
15924147 MGI
acts upstream of or within heart development IDA
IDA: 通过直接分析推断
32123163 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
24728959 MGI
acts upstream of or within inflammatory cell apoptotic process IDA
IDA: 通过直接分析推断
32123163 MGI
acts upstream of or within inflammatory response IDA
IDA: 通过直接分析推断
32123163 MGI
acts upstream of or within insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
22355763 MGI
acts upstream of or within insulin receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
29867121 MGI
acts upstream of or within insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
15924147 MGI
acts upstream of or within insulin secretion IMP
IMP: 通过突变表型推断
15924147 MGI
acts upstream of or within lung morphogenesis IGI
IGI: 通过遗传相互作用推断
31582725 MGI
acts upstream of or within lymphoid progenitor cell differentiation IMP
IMP: 通过突变表型推断
15713121 MGI
acts upstream of or within multicellular organism growth IGI
IGI: 通过遗传相互作用推断
24728959 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
22207709 MGI
acts upstream of or within neurogenesis IMP
IMP: 通过突变表型推断
22797695 MGI
acts upstream of or within peroxisome proliferator activated receptor signaling pathway IMP
IMP: 通过突变表型推断
22207709 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19389484 MGI
acts upstream of or within regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
19460132 MGI
acts upstream of or within respiratory system process IGI
IGI: 通过遗传相互作用推断
31582725 MGI
acts upstream of or within response to cAMP IMP
IMP: 通过突变表型推断
19460132 MGI
acts upstream of or within response to glucagon IMP
IMP: 通过突变表型推断
19460132 MGI
acts upstream of or within response to glucose IDA
IDA: 通过直接分析推断
32123163 MGI
acts upstream of or within response to insulin IDA
IDA: 通过直接分析推断
22355763 MGI
acts upstream of or within response to insulin IGI
IGI: 通过遗传相互作用推断
29867121 MGI
acts upstream of or within response to insulin IMP
IMP: 通过突变表型推断
15924147 MGI
acts upstream of or within response to wounding IMP
IMP: 通过突变表型推断
22207709 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
12874803 MGI
acts upstream of or within thyroid gland development IGI
IGI: 通过遗传相互作用推断
31582725 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA polymerase II transcription regulator complex IDA
IDA: 通过直接分析推断
19389484 MGI
part of SUMO ligase complex IDA
IDA: 通过直接分析推断
22207709 MGI
is active in cytoplasm IDA
IDA: 通过直接分析推断
15893306 MGI
located in male germ cell nucleus IDA
IDA: 通过直接分析推断
12032866 MGI
is active in mitochondrion IDA
IDA: 通过直接分析推断
15893306 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
15893306 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12032866 MGI
is active in nucleus IPI
IPI: 通过物理相互作用推断
16870469 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

high mobility group protein HMG-I/HMG-Y

high mobility group AT-hook protein 1

high mobility group protein A1

high mobility group protein I

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06230 HMGA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17912 Hmga1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24381 Hmga1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hmga1 NCBI NCBI:3159
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