2. Gene
  3. Hoxa2 - homeobox A2 Gene

Hoxa2 - homeobox A2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HOX1.11; Hox-1.11

基因 ID: 15399 | 基因类型: protein coding

关于 Hoxa2

功能概要

This gene is located in a cluster of developmentally and temporally regulated genes on chromosome 6 encoding proteins involved in pattern formation. These proteins contain a characteristic DNA-binding motif called a homeodomain and function in transcriptional regulation. There are four distinct clusters of related genes on chromosomes 2, 6, 11, and 15. The protein encoded by this gene is expressed in rhombomere 2 and is important for hindbrain formation in the early embryo. [provided by RefSeq, Mar 2013]

Hoxa2 基因产物(1)

mRNA Protein Name
NM_010451.2 NP_034581.1 homeobox protein Hox-A2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15634706 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15634706 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15634706 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within anterior/posterior pattern specification IMP
IMP: 通过突变表型推断
9367425 MGI
acts upstream of or within brain segmentation IMP
IMP: 通过突变表型推断
9367425 MGI
acts upstream of or within cell fate commitment IMP
IMP: 通过突变表型推断
7903600 MGI
acts upstream of or within cell fate determination IMP
IMP: 通过突变表型推断
16221728 MGI
acts upstream of or within cellular response to retinoic acid IDA
IDA: 通过直接分析推断
23723417 MGI
acts upstream of or within dorsal/ventral pattern formation IGI
IGI: 通过遗传相互作用推断
10230789 MGI
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: 通过突变表型推断
10230789 MGI
involved in embryonic skeletal system development IDA
IDA: 通过直接分析推断
25889273 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: 通过遗传相互作用推断
15634706 MGI
acts upstream of or within embryonic viscerocranium morphogenesis IMP
IMP: 通过突变表型推断
16221728 MGI
acts upstream of or within middle ear morphogenesis IGI
IGI: 通过遗传相互作用推断
15634706 MGI
acts upstream of or within middle ear morphogenesis IMP
IMP: 通过突变表型推断
15861402 MGI
acts upstream of or within motor neuron axon guidance IMP
IMP: 通过突变表型推断
9367425 MGI
involved in muscle structure development IDA
IDA: 通过直接分析推断
25889273 MGI
acts upstream of or within negative regulation of neuron differentiation IGI
IGI: 通过遗传相互作用推断
18164701 MGI
acts upstream of or within negative regulation of neuron differentiation IMP
IMP: 通过突变表型推断
18164701 MGI
acts upstream of or within negative regulation of osteoblast differentiation IDA
IDA: 通过直接分析推断
21324897 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15634706 MGI
acts upstream of neuron differentiation IMP
IMP: 通过突变表型推断
18164701 MGI
acts upstream of or within osteoblast development IGI
IGI: 通过遗传相互作用推断
16751105 MGI
acts upstream of or within pattern specification process IMP
IMP: 通过突变表型推断
7903600 MGI
involved in pharyngeal system development IDA
IDA: 通过直接分析推断
25889273 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18787068 MGI
acts upstream of or within rhombomere 2 development IMP
IMP: 通过突变表型推断
7508007 MGI
acts upstream of or within rhombomere 3 development IGI
IGI: 通过遗传相互作用推断
7508007 MGI
acts upstream of or within rhombomere 3 morphogenesis IMP
IMP: 通过突变表型推断
10230789 MGI
acts upstream of or within segment specification IMP
IMP: 通过突变表型推断
9367425 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
10536059 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

homeobox protein Hox-A2

homeo box A2

homeobox protein Hox-1.11

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06297 HOXA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22557 Hoxa2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hoxa2 NCBI NCBI:3199
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