2. Gene
  3. Hpgd - hydroxyprostaglandin dehydrogenase 15 (NAD) Gene

Hpgd - hydroxyprostaglandin dehydrogenase 15 (NAD) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：羟前列腺素脱氢酶 15 (NAD)

种属: Mus musculus

同用名: 15-PGDH

基因 ID: 15446 | 基因类型: protein coding

关于 Hpgd

Chromosome 8: 56,747,620-56,774,078 forward strand.GRCm39:CM001001.3

This gene has 1 transcript (splice variant), 204 orthologues and is associated with 9 phenotypes. Broad expression in lung adult (RPKM 76.), bladder adult (RPKM 5.8) and 17 other tissues.

功能概要

该基因编码的蛋白可启动 15-羟基前列腺素脱氢酶 (NAD+) 活性。参与动脉导管闭合。位于基底外侧质膜。以多种结构表达，包括消化系统；脉络丛;肱骨软骨凝结；鼻子;和泌尿系统。该基因的人类直系同源物与结肠癌和原发性肥大性骨关节病有关。与人 HPGD（15-羟基前列腺素脱氢酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables 15-hydroxyprostaglandin dehydrogenase (NAD+) activity. Involved in ductus arteriosus closure. Located in basolateral plasma membrane. Is expressed in several structures, including alimentary system; choroid plexus; humerus cartilage condensation; nose; and urinary system. Human ortholog(s) of this gene implicated in colon carcinoma and primary hypertrophic osteoarthropathy. Orthologous to human HPGD (15-hydroxyprostaglandin dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Hpgd 基因产物(1)

mRNA Protein Name
NM_008278.2 NP_032304.2 15-hydroxyprostaglandin dehydrogenase [NAD(+)]

Hpgd 蛋白结构

ADH_SDR_c_like

ADH_SDR_c_like: cd05323 (5 - 253)

  • 0
  • 100
  • 200
  • 269 a.a.
蛋白主名 其他名称

15-hydroxyprostaglandin dehydrogenase [NAD(+)]

15-hydroxyprostaglandin dehydrogenase

PGDH

eicosanoid/docosanoid dehydrogenase

prostaglandin dehydrogenase 1

重组 Hpgd 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75555 15-PGDH/HPGD Protein, Mouse (His) Q8VCC1 (M1-S269) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (14)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108259 HQL-79 Inhibitor 99.89% 否
HY-109134 Pizuglanstat Inhibitor 99.40% 否
HY-139972 PROTAC(H-PGDS)-7 Inhibitor 99.42% 否
HY-110167 TFC 007 Inhibitor ≥98.0% 否
HY-126134 HPGDS inhibitor 2 Inhibitor 99.72% 否
HY-12791 hPGDS-IN-1 Inhibitor 99.82% 否
HY-10439 HPGDS inhibitor 1 Inhibitor 99.04% 否
HY-146662 HPGDS inhibitor 3 Inhibitor / 否
HY-157577 PROTAC(H-PGDS)-8 Degrader / 否
HY-RS06338 HPGD Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06339 Hpgd Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06340 Hpgd Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06341 HPGDS Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-139171 F092 Inhibitor 99.79% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hpgd NCBI NCBI:3248
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