1. Gene
  2. Agfg1 - ArfGAP with FG repeats 1 Gene

Agfg1 - ArfGAP with FG repeats 1 Gene

种属: Mus musculus

同用名: Hrb; RAB; Rip; C130049H11Rik; D730048C23Rik

基因 ID: 15463 | 基因类型: protein coding

关于 Agfg1

功能概要

Predicted to enable DNA binding activity; GTPase activator activity; and metal ion binding activity. Acts upstream of or within acrosome assembly; intermediate filament organization; and spermatid nucleus differentiation. Located in cell projection; cytoplasmic vesicle; and neuronal cell body. Used to study male infertility. Orthologous to human AGFG1 (ArfGAP with FG repeats 1). [provided by Alliance of Genome Resources, Apr 2022]

Agfg1 基因产物(4)

mRNA Protein Name
NM_001310713.1 NP_001297642.1 arf-GAP domain and FG repeat-containing protein 1 isoform 2
NM_001347077.1 NP_001334006.1 arf-GAP domain and FG repeat-containing protein 1 isoform 3
NM_001368850.1 NP_001355779.1 arf-GAP domain and FG repeat-containing protein 1 isoform 4
NM_010472.3 NP_034602.1 arf-GAP domain and FG repeat-containing protein 1 isoform 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within acrosome assembly IMP
IMP: 通过突变表型推断
11711676 MGI
acts upstream of or within intermediate filament organization IMP
IMP: 通过突变表型推断
14724135 MGI
acts upstream of or within spermatid nucleus differentiation IMP
IMP: 通过突变表型推断
16765935 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell projection IDA
IDA: 通过直接分析推断
16421295 MGI
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
11711676 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
16421295 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

arf-GAP domain and FG repeat-containing protein 1

HIV-1 Rev binding protein

HIV-1 Rev-binding protein homolog

arf-GAP domain and FG repeats-containing protein 1

nucleoporin-like protein RIP

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Agfg1 NCBI NCBI:3267