2. Gene
  3. Hsd11b1 - hydroxysteroid 11-beta dehydrogenase 1 Gene

Hsd11b1 - hydroxysteroid 11-beta dehydrogenase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 15483 | 基因类型: protein coding

关于 Hsd11b1

功能概要

Enables 11-beta-hydroxysteroid dehydrogenase (NADP+) activity. Acts upstream of or within lung development. Predicted to be located in apical part of cell; nuclear membrane; and rough endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study cortisone reductase deficiency 2. Human ortholog(s) of this gene implicated in cortisone reductase deficiency; cortisone reductase deficiency 2; and obesity. Orthologous to human HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hsd11b1 基因产物(2)

mRNA Protein Name
NM_001044751.1 NP_001038216.1 11-beta-hydroxysteroid dehydrogenase 1
NM_008288.2 NP_032314.2 11-beta-hydroxysteroid dehydrogenase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 11-beta-hydroxysteroid dehydrogenase (NADP+) activity IDA
IDA: 通过直接分析推断
8940387 MGI
enables 11-beta-hydroxysteroid dehydrogenase (NADP+) activity IMP
IMP: 通过突变表型推断
12439781 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
12439781 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

11-beta-hydroxysteroid dehydrogenase 1

corticosteroid 11-beta-dehydrogenase isozyme 1

11-DH

11-beta-HSD1

11-beta-HSD1A/MCR

11-beta-hydroxysteroid dehydrogenase/microsomal carbonyl reductase

11beta-HSD-1

11beta-HSD1A

11beta-hydroxysteroid dehydrogenase type 1

7-oxosteroid reductase

Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06387 HSD11B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-167696 11β-HSD1-IN-16 Inhibitor / 否
HY-RS20631 Hsd11b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27140 Hsd11b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hsd11b1 NCBI NCBI:3290
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