2. Gene
  3. Cfh - complement factor H Gene

Cfh - complement factor H Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Fh; AMBP1; AMBP-1

基因 ID: 155012 | 基因类型: protein coding

关于 Cfh

功能概要

Predicted to enable several functions, including complement component C3b binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to interferon-gamma; and cellular response to lipopolysaccharide. Located in several cellular components, including extracellular space; nucleus; and plasma membrane. Used to study atypical hemolytic-uremic syndrome. Biomarker of amphetamine abuse; membranous glomerulonephritis; obstructive jaundice; proteinuria (multiple); and retinal degeneration. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; eye disease (multiple); hemolytic-uremic syndrome; lupus nephritis; and systemic lupus erythematosus. Orthologous to several human genes including CFH (complement Factor H). [provided by Alliance of Genome Resources, Apr 2022]

Cfh 基因产物(1)

mRNA Protein Name
NM_130409.2 NP_569093.2 complement factor H precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
20484586 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
12121434 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
12121434 RGD
involved in complement activation IEP
IEP: 通过表达模式推断
12911541 RGD
involved in regulation of complement activation IDA
IDA: 通过直接分析推断
12374811 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12911541 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

complement factor H

adrenomedullin binding protein-1

complement component factor H

complement inhibitory factor H

platelet complement factor H

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02561 CFH Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17522 Cfh Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23978 Cfh Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cfh NCBI NCBI:3075
Mus musculus Cfh NCBI NCBI:12628
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