2. Gene
  3. Hspb1 - heat shock protein 1 Gene

Hspb1 - heat shock protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 27kDa; Hsp25

基因 ID: 15507 | 基因类型: protein coding

关于 Hspb1

功能概要

Enables protein kinase C binding activity and protein kinase C inhibitor activity. Involved in negative regulation of protein kinase activity; positive regulation of cytokine production; and regulation of intracellular signal transduction. Acts upstream of or within negative regulation of apoptotic signaling pathway. Located in Z disc; nucleus; and plasma membrane. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and heart. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2F; distal hereditary motor neuropathy type 2B; pancreatic cancer; and sarcoma. Orthologous to human HSPB1 (heat shock protein family B (small) member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hspb1 基因产物(1)

mRNA Protein Name
NM_013560.2 NP_038588.2 heat shock protein beta-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein kinase C binding IDA
IDA: 通过直接分析推断
15731106 MGI
enables protein kinase C inhibitor activity IDA
IDA: 通过直接分析推断
15731106 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of apoptotic signaling pathway IDA
IDA: 通过直接分析推断
15731106 MGI
involved in negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
15731106 MGI
involved in negative regulation of protein kinase activity IDA
IDA: 通过直接分析推断
15731106 MGI
involved in positive regulation of interleukin-1 beta production IDA
IDA: 通过直接分析推断
12385642 MGI
involved in positive regulation of tumor necrosis factor production IDA
IDA: 通过直接分析推断
12385642 MGI
involved in regulation of canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
12385642 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
14627610 MGI
located in contractile muscle fiber IDA
IDA: 通过直接分析推断
14627610 MGI
is active in cornified envelope IDA
IDA: 通过直接分析推断
26644517 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
11774370 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
9122205 MGI
located in nucleus IDA
IDA: 通过直接分析推断
11774370 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
14627610 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

heat shock protein beta-1

HSP 25

HSP 27

growth-related 25 kDa protein

heat shock 25 kDa protein

heat shock 27 kDa protein

heat shock 27kDa protein 1

heat shock protein, 25 kDa

p25

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06438 HSPB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17913 Hspb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24382 Hspb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hspb1 NCBI NCBI:3315
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